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体外对内毒素透过非角化口腔黏膜的限速屏障进行定位研究。

Localization of rate-limiting barrier to penetration of endotoxin through nonkeratinized oral mucosa in vitro.

作者信息

Alfano M C, Drummond J F, Miller S A

出版信息

J Dent Res. 1975 Nov-Dec;54(6):1143-8. doi: 10.1177/00220345750540060801.

DOI:10.1177/00220345750540060801
PMID:1104674
Abstract

The penetration of tritiated bacterial endotoxin through nonkeratinized oral mucosal epithelium was studied using an in vitro model system and radioautographic tracer techniques. The basement membrane region of the epithelium was the rate-limiting barrier to penetration, and this barrier effect was independent of the direction and duration of penetration as well as any clearance effects of the vasculature.

摘要

使用体外模型系统和放射自显影示踪技术研究了氚标记的细菌内毒素透过非角化口腔黏膜上皮的情况。上皮的基底膜区域是渗透的限速屏障,且这种屏障作用与渗透方向、持续时间以及脉管系统的任何清除作用无关。

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Localization of rate-limiting barrier to penetration of endotoxin through nonkeratinized oral mucosa in vitro.体外对内毒素透过非角化口腔黏膜的限速屏障进行定位研究。
J Dent Res. 1975 Nov-Dec;54(6):1143-8. doi: 10.1177/00220345750540060801.
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