新生诱导小鼠嵌合体中耐受性的细胞基础。
Cellular basis of tolerance in neonatally induced mouse chimeras.
作者信息
Silvers W K, Elkins W L, Quimby F W
出版信息
J Exp Med. 1975 Nov 1;142(5):1312-5. doi: 10.1084/jem.142.5.1312.
Abstract
In mice, thymectomized as young adults, neonatally induced tolerance persists in the putative absence of cell chimerism. The finding provides evidence that a selective deficiency of specific clones of lymphocytes exists in transplantation tolerance when induced under the conditions of these experiments.
摘要
在幼年时进行胸腺切除的成年小鼠中，新生期诱导的耐受性在假定不存在细胞嵌合体的情况下依然存在。这一发现提供了证据，表明在这些实验条件下诱导移植耐受性时，存在特定淋巴细胞克隆的选择性缺陷。
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引用本文的文献
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Influence of size and gene dosage on the survival of skin allografts on rats rendered tolerant at birth.大小和基因剂量对出生时即产生耐受性的大鼠皮肤同种异体移植物存活的影响。
J Exp Med. 1983 Feb 1;157(2):591-9. doi: 10.1084/jem.157.2.591.
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Genetic regulation of the antibody response to H-2Db alloantigens in mice. II. Tolerance to non-H-2 determinants abolishes the antibody response to H-2Db in B10.A(5R) mice.小鼠对H-2Db同种异体抗原抗体反应的遗传调控。II. 对非H-2决定簇的耐受性消除了B10.A(5R)小鼠对H-2Db的抗体反应。
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本文引用的文献
1
THYMECTOMY IN NEWBORN AND ADULT MICE.新生小鼠和成年小鼠的胸腺切除术
Transplantation. 1963 Oct;1:521-5. doi: 10.1097/00007890-196301040-00011.
2
Effect of thymectomy in adult mice on immunological responsiveness.成年小鼠胸腺切除对免疫反应性的影响。
Nature. 1965 Dec 25;208(5017):1337-8. doi: 10.1038/2081337a0.
3
Soluble transplantation antigens. Further studies of their tolerogenic properties.
Transplantation. 1974 Dec;18(6):487-95. doi: 10.1097/00007890-197412000-00003.
4
Cell-mediated immunity and blocking serum activity before and after breakage of allograft tolerance in rats.大鼠同种异体移植耐受破坏前后的细胞介导免疫和阻断血清活性
Transplantation. 1973 Dec;16(6):610-20. doi: 10.1097/00007890-197312000-00013.
5
Importance of chimerism in maintaining tolerance of skin allografts in mice.嵌合现象在维持小鼠皮肤同种异体移植耐受性中的重要性。
J Immunol. 1973 Jul;111(1):65-71.
6
Immunity and tolerance: a unified concept.免疫与耐受：一个统一的概念。
Cell Immunol. 1971 Dec;2(6):670-89. doi: 10.1016/0008-8749(71)90014-1.
7
Deficit of specific thymus-dependent lymphocytes in transplantation tolerance in the rat.大鼠移植耐受中特定胸腺依赖性淋巴细胞的缺乏。
J Exp Med. 1973 Apr 1;137(4):1097-102. doi: 10.1084/jem.137.4.1097.
8
Graft-versus-host reactivity and inhibitory serum factors in allograft-tolerant chickens.同种异体移植耐受鸡中的移植物抗宿主反应性和抑制性血清因子
Transplantation. 1975 Jun;19(6):517-20.
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