Horner J M
School of Life Sciences, University of Surrey Roehampton, Whitelands College, London, UK.
Rev Environ Health. 2000 Jul-Sep;15(3):289-98. doi: 10.1515/reveh.2000.15.3.289.
Carbon monoxide (CO) is a colorless, nonirritating, odorless and tasteless gas. Carbon monoxide combines with hemoglobin far more readily than does oxygen, leading to tissue hypoxia. Thousands of people die annually from CO poisoning, and those recovering from acute exposure commonly suffer brain damage. Chronic poisoning is of particular concern to sufferers of coronary heart disease, pregnant women, and people with certain hematological disorders. Indoor emission sources, notably fuel-burning heating appliances, cause most unintentional deaths and cases of illness and should be the main focus of concern. Motor vehicle emissions pose a chronic health risk for occupationally exposed groups. Smoking is a major source of personal exposure. Recent exposure to CO is commonly evaluated by measuring blood carboxyhemoglobin levels, which are related to the concentration of atmospheric CO. Monitoring methods are reviewed here, and monitoring is considered in relation to air quality standards and guidelines. Finally, control measures for motor vehicles and indoor heating appliances are suggested.
一氧化碳(CO)是一种无色、无刺激性、无味且无味的气体。一氧化碳与血红蛋白结合的速度比氧气快得多,导致组织缺氧。每年有成千上万人死于一氧化碳中毒,急性中毒幸存者通常会遭受脑损伤。慢性中毒尤其值得冠心病患者、孕妇和某些血液系统疾病患者关注。室内排放源,尤其是燃烧燃料的取暖设备,是大多数意外死亡和疾病病例的原因,应成为主要关注焦点。机动车排放对职业暴露人群构成慢性健康风险。吸烟是个人接触一氧化碳的主要来源。近期一氧化碳暴露情况通常通过测量血液中碳氧血红蛋白水平来评估,该水平与大气中一氧化碳浓度相关。本文对监测方法进行了综述,并结合空气质量标准和指南对监测进行了探讨。最后,提出了机动车和室内取暖设备的控制措施。