Smadja P, Deguine O, Fraysse B, Bonafé A
Service de Neuroradiologie, Hôpital Purpan, Place du Docteur Baylac, Toulouse.
J Radiol. 1999 Sep;80(9):933-7.
Hearing preservation is one of the major goals of surgical resection of invasive cholesteatomas. Patients were prospectively evaluated using a 3D-CISS MR acquisition in order to improve the detection of perilymphatic fistulae.
16 patients (10 M, 6 F) presenting with a primary (1 case) or a secondary (post-otitis) middle ear cholesteatoma extending to the osseous labyrinth (as defined by HR-CT) were evaluated at MR (1.5 T Vision, Siemens). The 3D-CISS sequence (TR: 12.25 ms, TE: 5.90 ms, flip angle: 70 degrees, slice thickness: 1 mm, matrix: 307 x 512, FOV: 200) allowed detection of invasion of the membranous labyrinth using a 3 level grading scale: 1) normal fluids, 2) focal and 3) diffuse obliteration of labyrinthine fluid.
While CT showed a definite osseous labyrinthine fistula, the 3D-CISS sequence depicted either a normal membranous labyrinth (9 cases), a focal obliteration of the basal turn (1 case) or lateral semi-circular canal (3 cases) or a diffuse obliteration of the labyrinthine fluid (3 cases). Diffuse obliteration of the labyrinth fluid and 1 out 3 cases of focal obliteration of the semi-circular canal were found to have perilymphatic fistulae at surgery. None of the normal labyrinths were associated with perilymphatic fistula formation.
The 3D-CISS sequence allows a comprehensive preoperative evaluation of the membranous labyrinth. Loss of signal from the labyrinthine fluid due to invasion or compression of the membranous structures accounts for the lack of specificity of the technique.
听力保留是侵袭性胆脂瘤手术切除的主要目标之一。为了提高对迷路瘘管的检测,对患者进行了三维稳态构成干扰序列(3D-CISS)磁共振成像(MR)的前瞻性评估。
16例患者(10例男性,6例女性),患有原发性(1例)或继发性(中耳炎后)中耳胆脂瘤,病变延伸至骨迷路(根据高分辨率CT定义),接受了磁共振成像(1.5T Vision,西门子)检查。三维稳态构成干扰序列(TR:12.25毫秒,TE:5.90毫秒,翻转角:70度,层厚:1毫米,矩阵:307×512,视野:200)可使用三级分级量表检测膜迷路的侵犯情况:1)正常液体,2)局灶性,3)迷路液体弥漫性消失。
虽然CT显示有明确的骨迷路瘘管,但三维稳态构成干扰序列显示膜迷路正常(9例)、蜗底局灶性消失(1例)或外侧半规管局灶性消失(3例)或迷路液体弥漫性消失(3例)。迷路液体弥漫性消失以及3例半规管局灶性消失中的1例在手术中发现有外淋巴瘘。所有正常迷路均未出现外淋巴瘘形成。
三维稳态构成干扰序列可对膜迷路进行全面的术前评估。由于膜性结构的侵犯或压迫导致迷路液体信号消失,这是该技术缺乏特异性的原因。