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[阿根廷本土僧面猴中黄病毒抗体的流行情况]

[Prevalence of Flavivirus antibodies in Alouatta caraya primate autochthonous of Argentina].

作者信息

Contigiani M S, Fernández C, Spinsanti L I, Díaz G E

机构信息

Laboratorio de Arbovirus y Arenavirus, Instituto de Virología Dr. J. M. Vanella, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba.

出版信息

Medicina (B Aires). 2000;60(3):348-50.

PMID:11050814
Abstract

Flavivirus constitute a human health problem in our country. Primates are known to participate in the maintenance of Dengue and Yellow Fever viruses. However, these animals play a role which still remains to be determined in the maintenance of other viruses with potential pathogenicity for human beings and/or animals. Detección of antibodies was performed for different flavivirus in 105 sera samples of Alouatta caraya primates by the hemagglutination inhibition (HI) test. The neutralization (NT) test confirmed only infections caused by St. Louis Encephalitis (SLE) virus with a high prevalence in HI (35.23%) and NT (32.38%) antibodies. No antibody titres indicative of infections by Yellow Fever, Dengue and Bussuquara viruses were registered. Infection by the liheus virus could not be confirmed in these primates. There is a need for studies to detect new or reemergent viral infections in Argentina and the role that these primates could play in the maintenance of such infections.

摘要

黄病毒在我国构成人类健康问题。已知灵长类动物参与登革热病毒和黄热病病毒的传播。然而,在传播对人类和/或动物具有潜在致病性的其他病毒方面,这些动物所起的作用仍有待确定。通过血凝抑制(HI)试验对105份阿拉奥特卡拉亚灵长类动物血清样本中的不同黄病毒进行了抗体检测。中和(NT)试验仅证实了圣路易斯脑炎(SLE)病毒引起的感染,HI抗体(35.23%)和NT抗体(32.38%)的患病率很高。未记录到表明感染黄热病、登革热和布苏夸拉病毒的抗体滴度。在这些灵长类动物中无法证实感染了利厄斯病毒。有必要开展研究,以检测阿根廷新出现的或再次出现的病毒感染,以及这些灵长类动物在维持此类感染方面可能发挥的作用。

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