在巴西南部非人灵长类动物（阿拉奥特狨猴）黄热病监测期间，检测针对伊科阿拉西、伊列乌斯和圣路易斯脑炎虫媒病毒的抗体。
Detection of antibodies against Icoaraci, Ilhéus, and Saint Louis Encephalitis arboviruses during yellow fever monitoring surveillance in non-human primates (Alouatta caraya) in southern Brazil.
作者信息
Almeida Marco Antonio Barreto de, Santos Edmilson Dos, Cardoso Jáder da Cruz, Noll Carlos Alberto, Lima Marcelo de Moura, Silva Franko de Arruda E, Ferreira Milene Silveira, Martins Lívia Carício, Vasconcelos Pedro Fernando da Costa, Bicca-Marques Júlio César
机构信息
Centro Estadual de Vigilância em Saúde, Secretaria da Saúde do Estado do Rio Grande do Sul, Porto Alegre, Brazil.
Escola de Ciências, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil.
出版信息
J Med Primatol. 2019 Aug;48(4):211-217. doi: 10.1111/jmp.12417. Epub 2019 Apr 29.
BACKGROUND
Free-ranging non-human primates (NHPs) can host a variety of pathogenic microorganisms, such as arboviruses, which include the yellow fever virus (YFV). This study aimed to detect the circulation of YF and other arboviruses in three wild Alouatta caraya populations in forests in southern Brazil.
METHODS
We collected 40 blood and serum samples from 26 monkeys captured/recaptured up to four times from 2014 to 2016, searching for evidence of arboviruses by virus isolation, PCR, and neutralization tests.
RESULTS
Viral isolation and genome detection were negative; however, we detected neutralizing antibodies against the Saint Louis, Ilhéus, and Icoaraci viruses in three NHPs.
CONCLUSIONS
Saint Louis Encephalitis, Ilhéus, and Icoaraci viruses circulated recently in the region. Future studies should investigate the role of NHPs, other vertebrate hosts and wild vectors in the region's arbovirus circulation and the potential risks of the arboviruses to wildlife, domestic animals, and humans.
背景
自由放养的非人灵长类动物（NHPs）可携带多种致病微生物，如虫媒病毒，其中包括黄热病病毒（YFV）。本研究旨在检测巴西南部森林中三个野生褐吼猴种群中黄热病及其他虫媒病毒的传播情况。
方法
我们从2014年至2016年期间捕获/重新捕获的26只猴子身上采集了40份血液和血清样本，这些猴子最多被捕获/重新捕获了4次，通过病毒分离、聚合酶链反应（PCR）和中和试验寻找虫媒病毒的证据。
结果
病毒分离和基因组检测均为阴性；然而，我们在三只非人灵长类动物中检测到了针对圣路易斯、伊列乌斯和伊科阿拉西病毒的中和抗体。
结论
圣路易斯脑炎病毒、伊列乌斯病毒和伊科阿拉西病毒最近在该地区传播。未来的研究应调查非人灵长类动物、其他脊椎动物宿主和野生媒介在该地区虫媒病毒传播中的作用，以及这些虫媒病毒对野生动物、家畜和人类的潜在风险。
Zotero 插件