Corti M, Villafañe M F, Cermelj M, Candela M, Pérez Blanco R, Tezanos Pinto M
Instituto de Investigaciones Hematológicas, Academia Nacional de Medicina y Fundación de la Hemofilia, Buenos Aires.
Medicina (B Aires). 2000;60(3):351-3.
Intermediate and highly malignant non-Hodgkin and primary central nervous system lymphomas are marker diseases for AIDS. Cavum and oropharynx involvement by these tumors is uncommon. Although there are few cases reported in the literature, these may be primary localizations of the tumor. We present a hemophilic HIV+ patient with non-Hodgkin lymphoma of the cavum. The histologic diagnosis was high-grade, pleomorphic, centroblastic lymphoma. The patient was treated with chemotherapy plus intrathecal chemotherapy and highly active antiretroviral therapy (HAART). His evolution has been excellent. One year after diagnosis, the patient is asymptomatic with no evidence of residual tumor, and responding well to HAART.
中度和高度恶性非霍奇金淋巴瘤及原发性中枢神经系统淋巴瘤是艾滋病的标志性疾病。这些肿瘤累及蝶鞍和口咽并不常见。尽管文献报道的病例很少，但这些可能是肿瘤的原发性定位。我们报告一例患有蝶鞍非霍奇金淋巴瘤的血友病合并HIV阳性患者。组织学诊断为高级别、多形性、中心母细胞性淋巴瘤。该患者接受了化疗加鞘内化疗以及高效抗逆转录病毒治疗（HAART）。其病情进展良好。诊断后一年，患者无症状，无残留肿瘤迹象，且对HAART反应良好。
