Stuck B A, Maurer J T, Möckel C, Hörmann K
Universitäts-HNO-Klinik Mannheim.
Laryngorhinootologie. 2000 Sep;79(9):548-50. doi: 10.1055/s-2000-6938.
Superior laryngeal nerve neuralgia is a very rare disease typically associated with paroxysmal and lancinating pain mostly localised on one side of the laryngeal region and sometimes radiating into the homolateral jaw or ear. The condition is usually idiopathic and treated successfully with carbamazepine. Even if the symptoms are unusual or not typical for superior laryngeal nerve neuralgia, the condition should be considered as a possible diagnosis if there are no other pathological findings.
In October 1999, a 44-year old man presented a progressive dysphagia. Complaining about increasing problems in swallowing, he started refusing solid food and lost about 50 kg in two and a half years. In addition, he complained about persistent pain in the right laryngeal region, intensified by chewing or swallowing. Extensive investigations produced no pathological findings, especially no neoplastic process or other consuming diseases. After an injection of local anaesthetic near to the right hypothyroid membrane, the symptoms improved dramatically for a few hours and the diagnosis of superior laryngeal neuralgia was made. To confirm the diagnosis we injected sodium chloride as a placebo without any effect. The condition was successfully treated with 200 mg of carbamazepine three times daily without any major side effects.
Even if the symptoms are not typical and dysphagia and weight loss are the outstanding symptoms, superior laryngeal nerve neuralgia should be considered as the possible diagnosis, especially if no other pathological findings are revealed. Injection of local anesthetic is a valuable tool for diagnosing the disease.
喉上神经痛是一种非常罕见的疾病,通常表现为阵发性刺痛,主要局限于喉部区域的一侧,有时可放射至同侧颌部或耳部。该病通常为特发性,卡马西平治疗效果良好。即使症状不典型或不符合喉上神经痛的表现,但如果没有其他病理发现,仍应考虑该病为可能的诊断。
1999年10月,一名44岁男性出现进行性吞咽困难。他抱怨吞咽问题日益加重,开始拒绝固体食物,在两年半内体重减轻了约50公斤。此外,他还抱怨右喉区持续疼痛,咀嚼或吞咽时加重。广泛检查未发现病理结果,尤其是没有肿瘤病变或其他消耗性疾病。在右甲状腺下膜附近注射局部麻醉剂后,症状在数小时内显著改善,从而确诊为喉上神经痛。为了证实诊断,我们注射了氯化钠作为安慰剂,未产生任何效果。该患者每日三次服用200毫克卡马西平,病情得到成功治疗,且无任何严重副作用。
即使症状不典型,吞咽困难和体重减轻为突出症状,喉上神经痛仍应被视为可能的诊断,尤其是在未发现其他病理结果时。局部麻醉剂注射是诊断该病的一项有价值的手段。