Rotbart H A
Department of Pediatrics, University of Colorado Health Sciences Center, Denver 80262, USA.
Semin Neurol. 2000;20(3):277-92. doi: 10.1055/s-2000-9427.
Enteroviruses account for 85 to 95% of all cases of aseptic meningitis, but the arboviruses and herpes simplex virus are also important etiologic agents. Mumps, lymphocytic choriomeningitis virus, herpes zoster, human herpesvirus type 6, and influenza viruses are rare causes of meningitis. The virology, pathogenesis, epidemiology, clinical manifestations, diagnostic studies, and established and potential antiviral therapies for viral meningitis are discussed. A differential diagnosis of the aseptic meningitis syndrome is provided.
肠道病毒占所有无菌性脑膜炎病例的85%至95%，但虫媒病毒和单纯疱疹病毒也是重要的病原体。腮腺炎、淋巴细胞性脉络丛脑膜炎病毒、带状疱疹、人疱疹病毒6型和流感病毒是脑膜炎的罕见病因。本文讨论了病毒性脑膜炎的病毒学、发病机制、流行病学、临床表现、诊断研究以及已有的和潜在的抗病毒治疗方法。还提供了无菌性脑膜炎综合征的鉴别诊断。
