Agrawal S, Garg V K, Joshi A, Agarwalla A, Sah S P
Department of Dermatology and Venereology, B.P. Koirala Institute of Health Sciences, Dharan, Nepal.
J Dermatol. 2000 Sep;27(9):618-20. doi: 10.1111/j.1346-8138.2000.tb02240.x.
Vaccination against hepatitis B virus has rarely been associated with lichen planus. We report a case of this kind in a child from Nepal. A 12-year-old boy had developed generalized itchy violaceous papules and plaques six weeks after the second dose of hepatitis B virus vaccine. Serum HBsAg and HBeAb were negative, but HBsAb was positive. New crops of generalized, similar eruptions developed after the booster dose of vaccine. All the lesions resolved within three months of systemic steroid therapy. There was no recurrence after one year of follow up. Awareness of such an association is necessary, especially in children, because vaccination campaigns are increasing.
