Masui S, Sasaki T, Ishikawa H
Department of Biological Sciences, Graduate School of Science, University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
J Bacteriol. 2000 Nov;182(22):6529-31. doi: 10.1128/JB.182.22.6529-6531.2000.
Wolbachia species are intracellular bacteria known to cause reproductive abnormalities in their hosts. In this study, we identified Wolbachia genes encoding homologs to the type IV secretion system by which many pathogenic bacteria secrete macromolecules. The genes identified encoded most of the essential components of the secretion system and were cotranscribed as an operon.
沃尔巴克氏体属是已知会在其宿主中引起生殖异常的细胞内细菌。在本研究中,我们鉴定出了编码与IV型分泌系统同源物的沃尔巴克氏体基因,许多致病细菌通过该系统分泌大分子。鉴定出的基因编码了分泌系统的大部分必需组分,并作为一个操纵子共同转录。