Sá L R, DiLoreto C, Leite M C, Wakamatsu A, Santos R T, Catão-Dias J L
Departamento de Patologia, Faculdade de Medicina Veterinária e Zootecnia, Cidade Universitária, São Paulo, Brasil.
Vet Pathol. 2000 Sep;37(5):492-6. doi: 10.1354/vp.37-5-492.
Oral focal epithelial hyperplasia is a rare and seldom reported disease in animals and humans induced by a papillomavirus. The present report is the first description of this disease in a Neotropical primate, a howler monkey (Alouatta fusca). The diagnosis was based on gross and microscopic findings. The generic papillomavirus antigen was identified by immunohistochemistry and was found not to be related to any human papillomavirus DNA tested by in situ hybridization. This virus is probably a specific papillomavirus of the howler monkey (HMPV).
口腔局灶性上皮增生是一种由乳头瘤病毒引起的在动物和人类中均罕见且鲜有报道的疾病。本报告首次描述了这种疾病在一种新热带灵长类动物——吼猴（Alouatta fusca）中的情况。诊断基于大体和显微镜检查结果。通过免疫组织化学鉴定出了一般的乳头瘤病毒抗原，并且发现其与通过原位杂交检测的任何人类乳头瘤病毒DNA均无关联。这种病毒可能是吼猴特有的乳头瘤病毒（HMPV）。
