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肾上腺素对人血小板单胺氧化酶活性的影响。

The effect of adrenaline on human platelet MAO activity.

作者信息

Gentil V, Greenwood M H, Lader M H

出版信息

Psychopharmacologia. 1975 Oct 31;44(2):187-90. doi: 10.1007/BF00421008.

DOI:10.1007/BF00421008
PMID:1105633
Abstract

Platelet monoamine oxidase (MAO) activity was determined before and after the subcutaneous administration of adrenaline to nine healthy volunteers. Significant increases were found 15 min and 1 hr after adrenaline in the enzymatic activity with benzylamine acting as substrate. Increases were also found in all but two samples in the activity towards tyramine. Such increases may be part of a general response to "stress", and, if so, need to be taken into account when interpreting changes in platelet MAO activity in psychiatric patients.

摘要

对9名健康志愿者皮下注射肾上腺素前后测定了血小板单胺氧化酶(MAO)活性。以苄胺为底物时,肾上腺素注射后15分钟和1小时酶活性显著增加。除两个样本外,对酪胺的活性在所有样本中也有所增加。这种增加可能是对“应激”的一般反应的一部分,如果是这样,在解释精神病患者血小板MAO活性变化时需要考虑到这一点。

相似文献

1
The effect of adrenaline on human platelet MAO activity.肾上腺素对人血小板单胺氧化酶活性的影响。
Psychopharmacologia. 1975 Oct 31;44(2):187-90. doi: 10.1007/BF00421008.
2
The effects of adrenaline injections on human platelet monoamine oxidase and related measures.肾上腺素注射对人体血小板单胺氧化酶及相关指标的影响。
Psychopharmacology (Berl). 1976 Nov 10;50(2):187-92. doi: 10.1007/BF00430491.
3
Altered platelet monoamine oxidase activity in affective disorders.情感障碍中血小板单胺氧化酶活性的改变。
Psychol Med. 1979 Nov;9(4):729-36. doi: 10.1017/s0033291700034048.
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The effect of subcutaneous injections of adrenaline on platelet MAO activity [proceedings].皮下注射肾上腺素对血小板单胺氧化酶活性的影响[会议论文集]
Br J Pharmacol. 1976 Oct;58(2):291P-292P.
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Monoamine oxidase (MAO) of platelets, plasma, lymphocytes and granulocytes in schizophrenia.精神分裂症患者血小板、血浆、淋巴细胞及粒细胞中的单胺氧化酶(MAO)
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[Monoamine oxidase (XXXVI). Characteristics of benzylamine oxidase in the dog serum].[单胺氧化酶(XXXVI)。犬血清中苄胺氧化酶的特性]
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Elevation of human plasma and platelet amine oxidase activity in response to intravenous dopamine.静脉注射多巴胺后人体血浆和血小板胺氧化酶活性的升高。
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Effects of adrenaline administration on platelet MAO of anxious and normal subjects.肾上腺素给药对焦虑症患者和正常人血小板单胺氧化酶的影响。
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Platelet monamine oxidase in chronic schizophrenia. Some enzyme characteristics relevant to reduced activity.慢性精神分裂症中的血小板单胺氧化酶。一些与活性降低相关的酶特性。
Arch Gen Psychiatry. 1976 Nov;33(11):1377-81. doi: 10.1001/archpsyc.1976.01770110105011.

引用本文的文献

1
[Interrelation between the activity of the monoamine oxidase enzyme, personality and physical state among young police officers].[青年警察单胺氧化酶活性、个性与身体状况之间的相互关系]
J Psychiatry Neurosci. 1994 Jul;19(4):289-94.
2
Platelet monoamine oxidase activity in megaloblastic anaemia.巨幼细胞贫血中的血小板单胺氧化酶活性
J Clin Pathol. 1980 Oct;33(10):963-5. doi: 10.1136/jcp.33.10.963.
3
The specific activity of platelet monoamine oxidase varies with platelet count during severe exercise and noradrenaline infusion.

本文引用的文献

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The effect of subcutaneous injections of adrenaline on platelet MAO activity [proceedings].皮下注射肾上腺素对血小板单胺氧化酶活性的影响[会议论文集]
Br J Pharmacol. 1976 Oct;58(2):291P-292P.
6
The effects of adrenaline injections on human platelet monoamine oxidase and related measures.肾上腺素注射对人体血小板单胺氧化酶及相关指标的影响。
Psychopharmacology (Berl). 1976 Nov 10;50(2):187-92. doi: 10.1007/BF00430491.
7
Substrate-typic changes of platelet monoamine oxidase activity in sub-types of schizophrenia.精神分裂症亚型中血小板单胺氧化酶活性的底物类型变化
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Monoamine oxidase activity in different density gradient fractions of human platelets.人血小板不同密度梯度组分中的单胺氧化酶活性
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An enzyme (MAO) defect on the platelets in migraine.偏头痛患者血小板上的一种酶(单胺氧化酶)缺陷。
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5
Effect of psychosocial stimulation on the enzymes involved in the biosynthesis and metabolism of noradrenaline and adrenaline.心理社会刺激对去甲肾上腺素和肾上腺素生物合成及代谢相关酶的影响。
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Increased monoamine oxidase activity following repeated electroshock seizures.反复电休克惊厥后单胺氧化酶活性增加。
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7
Reduced monoamine oxidase activity in blood platelets from bipolar depressed patients.双相抑郁症患者血小板中单胺氧化酶活性降低。
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The effects of metopirone and adrenalectomy on the regulation of the enzymes monoamine oxidase and catechol-O-methyl transferase in different brain regions.
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9
Proceedings: Multiple forms of MAO: some in vivo correlations.会议论文:单胺氧化酶的多种形式:一些体内相关性
Psychopharmacol Bull. 1974 Jul;10(3):5-6.
10
Proceedings: Comparison of MAO substrate activities in twins, schizophrenics, depressives, and controls.论文集:双胞胎、精神分裂症患者、抑郁症患者及对照组中MAO底物活性的比较。
Psychopharmacol Bull. 1974 Jul;10(3):10.