Koh C K, Hew F L, Chiu C L
Department of Medicine, Faculty of Medicine, University of Malaya, Malaysia.
Ann Acad Med Singap. 2000 Jul;29(4):528-30.
The association of chronic urticaria and thyroid autoimmunity is not well recognised and the potential use of thyroxine in the treatment of chronic urticaria in patients with thyroid autoimmunity is even less well known.
We report a case of chronic urticaria in an euthyroid patient with evidence of significantly elevated levels of thyroglobulin and microsomal antibodies.
Treatment with thyroxine has brought about clinical remission of the chronic urticaria but no change in the thyroid antibody levels could be demonstrated.
Patients with chronic urticaria should be screened for evidence of thyroid autoimmunity. A closely monitored trial of thyroxine therapy for those who have thyroid autoimmunity can be rewarding.
慢性荨麻疹与甲状腺自身免疫之间的关联尚未得到充分认识,而甲状腺素在治疗甲状腺自身免疫患者慢性荨麻疹方面的潜在用途更是鲜为人知。
我们报告一例甲状腺功能正常的慢性荨麻疹患者,其甲状腺球蛋白和微粒体抗体水平显著升高。
甲状腺素治疗使慢性荨麻疹临床缓解,但甲状腺抗体水平无变化。
慢性荨麻疹患者应筛查甲状腺自身免疫证据。对有甲状腺自身免疫的患者进行密切监测的甲状腺素治疗试验可能会有收获。