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门静脉血栓形成患者的溶栓治疗:病例报告及文献综述

Thrombolytic therapy in patients with portal vein thrombosis: case report and review of the literature.

作者信息

Schäfer C, Zundler J, Bode J C

机构信息

The Robert-Bosch-Krankenhaus Stuttgart, Department of Internal Medicine, Germany.

出版信息

Eur J Gastroenterol Hepatol. 2000 Oct;12(10):1141-5. doi: 10.1097/00042737-200012100-00012.

DOI:10.1097/00042737-200012100-00012
PMID:11057461
Abstract

A 29-year-old male patient with Crohn's disease of the terminal ileum and previous abdominal surgery was admitted because of severe abdominal pain and signs of bacterial sepsis. The diagnosis of portal vein thrombosis and multiple liver abscesses due to Streptococcus intermedius septicaemia was made and antibiotic therapy was instituted immediately. As high-dose heparin therapy was ineffective, urokinase was administered intravenously over a total of 7 days. Within 2 days, the patient's symptoms completely subsided. Colour duplex ultrasonography revealed complete recanalization of the main stem of the portal vein; the right branch of the portal vein, however, remained occluded. Other case reports on thrombolytic therapy in patients with portal vein thrombosis are reviewed.

摘要

一名29岁男性患者,患有回肠末端克罗恩病且曾接受过腹部手术,因严重腹痛和细菌败血症迹象入院。诊断为门静脉血栓形成以及由中间型链球菌败血症引起的多发性肝脓肿,并立即开始抗生素治疗。由于大剂量肝素治疗无效,总共静脉注射尿激酶7天。两天内,患者症状完全消退。彩色双功超声检查显示门静脉主干完全再通;然而,门静脉右支仍闭塞。本文对门静脉血栓形成患者溶栓治疗的其他病例报告进行了综述。

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