Marchesi D G
Department of Orthopaedic Surgery, Jewish General Hospital, Montreal, Canada.
Eur Spine J. 2000 Oct;9(5):372-8. doi: 10.1007/s005860000203.
Vertebral arthrodesis is one of the most commonly performed, yet incompletely understood, procedures in spinal surgery. Despite major progress in internal fixation techniques, the high rate of nonunions indicates that physiologic, biologic and molecular events that are crucial to this process are not well known. This article will analyze the general biology of bone regeneration, and particularly discuss the properties and use of various bone graft materials and graft substitutes.
椎体融合术是脊柱外科中最常开展但尚未被完全理解的手术之一。尽管内固定技术取得了重大进展，但不愈合率居高不下，这表明对该过程至关重要的生理、生物和分子事件尚不清楚。本文将分析骨再生的一般生物学原理，尤其会讨论各种骨移植材料和移植替代物的特性及应用。
