Aksoy H, Aksoy Y, Akçay F, Kurtul N
Department of Biochemistry, Medical School, Atatürk University, Erzurum, Turkey.
Int Urol Nephrol. 2000;32(1):81-3. doi: 10.1023/a:1007116419976.
We measured the circulatory levels of nitric oxide and estradiol in men over 50 years with estrogenisation findings. We investigated relation between nitric oxide, which is the principal signal for relaxation of vascular smooth muscle cells, and estradiol levels in serum in men over 50 years with estrogenisation. This study included 14 men with (group 1) and 20 without estrogenisation findings (group 2). Mean nitric oxide and estradiol levels were found to be significantly lower in group 2 than group 1. Group 2 had lower levels sex-hormone binding globin and higher both systolic and diastolic blood pressure values than group 1. There was a significant correlation between nitric oxide and estradiol in esrogenisation group.
我们测量了50岁以上有雌激素化表现男性体内一氧化氮和雌二醇的循环水平。我们研究了作为血管平滑肌细胞舒张主要信号的一氧化氮与50岁以上有雌激素化表现男性血清中雌二醇水平之间的关系。本研究纳入了14名有雌激素化表现的男性（第1组）和20名无雌激素化表现的男性（第2组）。发现第2组的一氧化氮和雌二醇平均水平显著低于第1组。第2组的性激素结合球蛋白水平较低，收缩压和舒张压值均高于第1组。雌激素化组中一氧化氮和雌二醇之间存在显著相关性。
