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西班牙人群代表性样本中HIV和HTLV的血清流行率。

Seroprevalence of HIV and HTLV in a representative sample of the Spanish population.

作者信息

Castilla J, Pachón I, González M P, Amela C, Muñoz L, Tello O, Noguer I, de Ory F, León P, Alonso M, Gil E, García-Sáiz A

机构信息

National Centre for Epidemiology, Centro Nacional de Epidemiología, Madrid, Spain.

出版信息

Epidemiol Infect. 2000 Aug;125(1):159-62. doi: 10.1017/s0950268899004203.

Abstract

HIV and HTLV seroprevalence was determined by means of unlinked anonymous testing of 2144 sera, originally obtained from primary care patients by representative sampling of the Spanish population aged 15-39 years in 1996. HIV-1 seroprevalence was 4.3 per 1000 population in the 15-39 years age group [95% confidence interval (CI), 1.5-10.7] and 5.6 per 1000 (95% CI, 1.8-15.3) in the 20-39 years age group. Seroprevalence proved higher in males and urban residents. No antibodies to HIV-2 and HTLV-I were detected in any of the sera studied. However, presence of antibodies to HTLV-II was confirmed in one serum sample, while HTLV seroreactivity, though detected in another, could not be typed. The two HTLV-positive results equated to a seroprevalence of 1.9 per 1000 in the 20-39 years age group (95% CI, 0.3-8.6). HIV-I seroprevalence was consistent with previous estimates yielded by back-calculation. The level of HTLV seroprevalence found suggests endemicity.

摘要

通过对2144份血清进行非关联匿名检测来确定HIV和HTLV的血清流行率,这些血清最初于1996年通过对西班牙15 - 39岁人群进行代表性抽样从初级保健患者中获取。15 - 39岁年龄组的HIV - 1血清流行率为每1000人中有4.3例[95%置信区间(CI),1.5 - 10.7],20 - 39岁年龄组为每1000人中有5.6例(95%CI,1.8 - 15.3)。血清流行率在男性和城市居民中更高。在所研究的任何血清中均未检测到HIV - 2和HTLV - I的抗体。然而,在一份血清样本中确认存在HTLV - II抗体,而在另一份样本中虽检测到HTLV血清反应性,但无法分型。这两个HTLV阳性结果相当于20 - 39岁年龄组的血清流行率为每1000人中有1.9例(95%CI,0.3 - 8.6)。HIV - I血清流行率与先前通过反向计算得出的估计值一致。所发现的HTLV血清流行率水平表明存在地方流行情况。

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