Castilla J, Pachón I, González M P, Amela C, Muñoz L, Tello O, Noguer I, de Ory F, León P, Alonso M, Gil E, García-Sáiz A
National Centre for Epidemiology, Centro Nacional de Epidemiología, Madrid, Spain.
Epidemiol Infect. 2000 Aug;125(1):159-62. doi: 10.1017/s0950268899004203.
HIV and HTLV seroprevalence was determined by means of unlinked anonymous testing of 2144 sera, originally obtained from primary care patients by representative sampling of the Spanish population aged 15-39 years in 1996. HIV-1 seroprevalence was 4.3 per 1000 population in the 15-39 years age group [95% confidence interval (CI), 1.5-10.7] and 5.6 per 1000 (95% CI, 1.8-15.3) in the 20-39 years age group. Seroprevalence proved higher in males and urban residents. No antibodies to HIV-2 and HTLV-I were detected in any of the sera studied. However, presence of antibodies to HTLV-II was confirmed in one serum sample, while HTLV seroreactivity, though detected in another, could not be typed. The two HTLV-positive results equated to a seroprevalence of 1.9 per 1000 in the 20-39 years age group (95% CI, 0.3-8.6). HIV-I seroprevalence was consistent with previous estimates yielded by back-calculation. The level of HTLV seroprevalence found suggests endemicity.
通过对2144份血清进行非关联匿名检测来确定HIV和HTLV的血清流行率,这些血清最初于1996年通过对西班牙15 - 39岁人群进行代表性抽样从初级保健患者中获取。15 - 39岁年龄组的HIV - 1血清流行率为每1000人中有4.3例[95%置信区间(CI),1.5 - 10.7],20 - 39岁年龄组为每1000人中有5.6例(95%CI,1.8 - 15.3)。血清流行率在男性和城市居民中更高。在所研究的任何血清中均未检测到HIV - 2和HTLV - I的抗体。然而,在一份血清样本中确认存在HTLV - II抗体,而在另一份样本中虽检测到HTLV血清反应性,但无法分型。这两个HTLV阳性结果相当于20 - 39岁年龄组的血清流行率为每1000人中有1.9例(95%CI,0.3 - 8.6)。HIV - I血清流行率与先前通过反向计算得出的估计值一致。所发现的HTLV血清流行率水平表明存在地方流行情况。