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[炎性假瘤患者的肋骨溶骨性病变和多发性肝脏新生物]

[Costal osteolytic lesions and multiple hepatic neoformations in a patient with inflammatory pseudotumor].

作者信息

Gabrielli G B, Casaril M, Stanzial A M, Corrocher R

机构信息

Dipartimento di Medicina Clinica e Sperimentale, Università degli Studi di Verona.

出版信息

Ann Ital Med Int. 2000 Jul-Sep;15(3):226-31.

Abstract

Inflammatory pseudotumor is a rare disease, that is regarded as a benign reactive inflammatory process, although its etiology and pathogenesis are still unknown. The liver is one of the organs most frequently involved, but inflammatory pseudotumors have been reported in many other sites in the body. Inflammatory pseudotumor of the liver presents as a solitary or, less frequently, multiple space-occupying lesion, which the common imaging techniques do not clearly distinguish from primitive or metastatic hepatic malignancies. Biopsy of the lesion is therefore necessary for diagnosis. The case of inflammatory pseudotumor described here presented with radiologic features of multiple solid space-occupying lesions in the liver, associated with multiple osteolytic lesions in the ribs. Such an association, very suggestive of malignancy, has not yet been reported for inflammatory pseudotumors. Optimum management of this disease has not yet been standardized. The majority of patients are treated by hepatic resection, although spontaneous regression has also been described. In our case, rapid improvement of both hepatic and costal lesions was observed, although the patient did not receive any specific treatment.

摘要

炎性假瘤是一种罕见疾病,尽管其病因和发病机制尚不清楚,但被视为一种良性反应性炎症过程。肝脏是最常受累的器官之一,但在身体的许多其他部位也有炎性假瘤的报道。肝脏炎性假瘤表现为单个或较少见的多个占位性病变,普通成像技术无法将其与原发性或转移性肝恶性肿瘤清楚区分。因此,病变活检对于诊断是必要的。本文所述的炎性假瘤病例表现为肝脏多个实性占位性病变的放射学特征,并伴有肋骨多处溶骨性病变。这种关联非常提示恶性肿瘤,而炎性假瘤尚未有过此类报道。该疾病的最佳治疗方法尚未标准化。大多数患者接受肝切除术治疗,尽管也有自发消退的描述。在我们的病例中,尽管患者未接受任何特殊治疗,但肝脏和肋骨病变均迅速改善。

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