安定（地西泮）延长皮肤同种异体移植物存活时间
Prolongation of skin allograft survival by Valium (diazepam).
作者信息
Ballantyne D L, Harper A D
出版信息
Transplant Proc. 1975 Dec;7(4):581-6.
PMID:1105915
Abstract
The survival of rat skin allografts was significantly increased by repeated intraperitoneal injections of 2.5 mg Valium (diazepam) into hosts. In addition, in vivo pretreatment of the donor animals at this dose level decreased the intensity of the recipients' immune responses to skin allografts. In vitro exposure of skin grafts to Valium also prolonged allograft survival.
摘要
通过向宿主反复腹腔注射2.5毫克安定（地西泮），大鼠皮肤同种异体移植物的存活时间显著延长。此外，在此剂量水平对供体动物进行体内预处理可降低受体对皮肤同种异体移植物的免疫反应强度。将皮肤移植物在体外暴露于安定也能延长同种异体移植物的存活时间。
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