Röckel A, Hennemann H, Sternagel-Haase A, Heidland A
Eur J Clin Invest. 1979 Feb;9(1):23-7. doi: 10.1111/j.1365-2362.1979.tb01663.x.
Autonomic function in patients with uraemia treated conservatively, by haemodialysis, and by transplantation was evaluated by the pupillary reaction to tyramine, the Valsalva manoeuvre and a postural tolerance test. The pupillary reaction to tyramine is diminished in haemodialysis patients compared with control subjects. Renal transplantation improves, but does not correct the pupillary reaction to tyramine. The frequency of the diminished response roughly correlates with the degree of renal insufficiency, with results of a Valsalva manoeuvre, and with postural tolerance tests. Our data show that uraemic autonomic dysfunction is improved by successful renal transplantation, but not by adequate haemodialysis.
通过对去氧肾上腺素的瞳孔反应、瓦尔萨尔瓦动作和姿势耐力测试，评估了保守治疗、血液透析和移植治疗的尿毒症患者的自主神经功能。与对照受试者相比，血液透析患者对去氧肾上腺素的瞳孔反应减弱。肾移植可改善但不能纠正对去氧肾上腺素的瞳孔反应。反应减弱的频率大致与肾功能不全程度、瓦尔萨尔瓦动作结果和姿势耐力测试结果相关。我们的数据表明，成功的肾移植可改善尿毒症自主神经功能障碍，但充分的血液透析则不能。
