内脏痛觉感受
Visceral nociception.
作者信息
Westlund K N
机构信息
Department of Anatomy and Neurosciences, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555, USA.
出版信息
Curr Rev Pain. 2000;4(6):478-87. doi: 10.1007/s11916-000-0072-9.
Abstract
Visceral pain is of great concern to the medical community because it remains particularly resistant to current clinical treatments. A serendipitous and initially unexplainable clinical finding that a punctate midline dorsal column lesion is effective in eliminating visceral pain, however, has initiated a resurgence of interest in the study of the basic mechanisms of visceral nociception. Clinical and anatomic findings have determined that visceral pain either of thoracic or pelvic origin can be relieved by carefully placed lesions directed at the lateral edge or the medial edge of the gracile fasciculus, respectively. Studies are demonstrating that visceral pain is quite unique from cutaneous pain.
摘要
内脏痛备受医学界关注，因为它对当前的临床治疗仍具有很强的抗性。然而，一个偶然且起初无法解释的临床发现——点状的中线背柱损伤可有效消除内脏痛，引发了人们对内脏痛觉基本机制研究兴趣的再度兴起。临床和解剖学研究结果已确定，分别通过精准定位在薄束外侧缘或内侧缘的损伤，可缓解源自胸部或盆腔的内脏痛。研究表明，内脏痛与皮肤痛截然不同。
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