Kilburn K H
Environmental Sciences Laboratory, University of Southern California, School of Medicine, Los Angeles 90033, USA.
Am J Med Sci. 2000 Oct;320(4):249-54. doi: 10.1097/00000441-200010000-00005.
The objective was to measure and compare the neurobehavioral and respiratory effects of exposures to indoor air in people living in manufactured homes and occupying buildings during renovation and compare them with effects on subjects exposed to formaldehyde at work.
Ten people living in manufactured homes and 10 people exposed to chemicals during renovation of their offices or homes had measurements made of balance, visual fields, reaction time, hearing, grip strength, and vibration sense. Psychological measurements included cognition, recall, perceptual motor speed, long-term memory, and mood states.
Exposures to indoor air were associated with abnormal simple and choice reaction time, abnormal balance with the eyes open and with the eyes closed, abnormalities of color confusion index, scotoma in visual fields, reduced verbal recall, digit symbol score, and elevated abnormal moods. The effects on the two groups of 10 were similar and resembled those from formaldehyde exposure but with less cognitive impairment.
Adverse effects from indoor air in manufactured homes and during renovations were less severe but similar to those from occupational formaldehyde exposures. This suggests that formaldehyde has a major role in health problems from indoor air.
目的是测量和比较居住在装配式房屋中的人和在建筑物翻新期间居住在建筑物内的人接触室内空气后的神经行为和呼吸影响，并将其与工作中接触甲醛的受试者的影响进行比较。
对10名居住在装配式房屋中的人和10名在办公室或家中翻新期间接触化学物质的人进行了平衡、视野、反应时间、听力、握力和振动觉的测量。心理测量包括认知、回忆、感知运动速度、长期记忆和情绪状态。
接触室内空气与简单和选择反应时间异常、睁眼和闭眼时平衡异常、颜色混淆指数异常、视野暗点、言语回忆减少、数字符号得分降低以及异常情绪升高有关。对两组各10人的影响相似，类似于甲醛暴露的影响，但认知障碍较轻。
装配式房屋内和翻新期间室内空气的不良影响虽不那么严重，但与职业性甲醛暴露的影响相似。这表明甲醛在室内空气污染导致的健康问题中起主要作用。
