Charous B L, Schuenemann P J, Swanson M C
Milwaukee Medical Clinic, Advanced Healthcare, SC, Wisconsin, USA.
Ann Allergy Asthma Immunol. 2000 Oct;85(4):285-90. doi: 10.1016/S1081-1206(10)62531-8.
Prompted by worsening asthma in a dental assistant with latex allergy and occupational asthma while under personal latex precautions, we confirmed continuing latex aeroallergen exposure.
To determine the source of latex aeroallergen and ascertain the effects of site-wide substitution of nonpowdered low allergen latex glove in a health care site.
Using a volumetric sampler, baseline latex aeroallergen levels were measured in rooms where she worked and nearby rooms, as well as shared X-ray, laboratory, and waiting rooms. Allergen levels were measured in upholstery fabric samples, ventilation duct dust, and latex gloves. Alterations in aeroallergen levels following change of glove types were prospectively determined.
Baseline latex aeroallergen levels ranged from 6 to 25 ng/m3 in the patient's work areas and in other rooms from 29 to 90 ng/m3 during work hours. Latex antigen was found in three brands of powdered latex gloves (chi = 1,156 microg/g) used in the nearby opertories and the hygiene room, and in upholstery fabric, carpet dust, but not ventilation duct dust. In the absence of any other control measures, airborne latex became undetectable (<5 ng/m3) with exclusive use of nonpowdered latex gloves.
Latex aeroallergen is primarily generated by active glove use; carpeting and fabric upholstery can serve as important aeroallergen repositories. Site-wide substitution of nonpowdered latex gloves eliminates detectable latex aeroallergen.
一名患有乳胶过敏和职业性哮喘的牙科助理在采取个人乳胶防护措施期间哮喘病情恶化，促使我们确认其持续接触乳胶空气变应原。
确定乳胶空气变应原的来源，并确定在一个医疗机构中全面更换为无粉低变应原乳胶手套的效果。
使用体积采样器，在她工作的房间、附近的房间以及共用的X光室、实验室和候诊室测量乳胶空气变应原的基线水平。在室内装饰织物样本、通风管道灰尘和乳胶手套中测量变应原水平。前瞻性地确定更换手套类型后空气变应原水平的变化。
患者工作区域的乳胶空气变应原基线水平在6至25 ng/m3之间，工作时间内其他房间的基线水平在29至90 ng/m3之间。在附近的手术室和卫生室使用的三个品牌的粉状乳胶手套（χ = 1,156微克/克）以及室内装饰织物、地毯灰尘中发现了乳胶抗原，但在通风管道灰尘中未发现。在没有任何其他控制措施的情况下，仅使用无粉乳胶手套时，空气中的乳胶变得无法检测到（<5 ng/m3）。
乳胶空气变应原主要由积极使用手套产生；地毯和织物内饰可作为重要的空气变应原储存库。全面更换为无粉乳胶手套可消除可检测到的乳胶空气变应原。
