Friedman C, Gaeke M E, Fang V, Kim M H
Am J Obstet Gynecol. 1976 Jan 1;124(1):75-9. doi: 10.1016/0002-9378(76)90014-4.
Pituitary responses to luteinizing-hormone-releasing-hormone (LRH) in the postpartum periods were studied. Following a subcutaneous injection of 100 mug of synthetic LRH to postpartum subjects, no statistically significant changes in the levels of LH and FSH could be demonstrated in five subjects on postpartum day 1 or 3 and the three subjects on postpartum day 8. A normal elevation of LH and FSH following LRH was demonstrated in one subject 36 days post partum. The findings are in agreement with previous studies demonstrating a persistence of pituitary suppression during the early postpartum period. No correlation could be drawn between the pituitary responses to LRH and the plasma levels of estradiol-17 beta and progesterone.
研究了产后时期垂体对促黄体生成激素释放激素（LRH）的反应。对产后受试者皮下注射100微克合成LRH后，产后第1天或第3天的5名受试者以及产后第8天的3名受试者中，LH和FSH水平无统计学上的显著变化。一名产后36天的受试者在注射LRH后出现了LH和FSH的正常升高。这些发现与先前的研究一致，表明产后早期垂体抑制持续存在。垂体对LRH的反应与血浆雌二醇-17β和孕酮水平之间无相关性。
