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贾第虫病的当前观点

Current perspectives on giardiasis.

作者信息

Fisher C H, Oh K S, Bayless T M, Siegelman S S

出版信息

Am J Roentgenol Radium Ther Nucl Med. 1975 Sep;125(1):207-17. doi: 10.2214/ajr.125.1.207.

DOI:10.2214/ajr.125.1.207
PMID:1106221
Abstract

Giardia lamblia infestation can cause severe diarrhea and malabsorption, and the diagnosis is usually made by identification of cysts in the feces, but small intestinal biopsy or smears may be required. A wide spectrum of roentgen changes may be seen. In patients with a normal immune status, the small bowel is normal or shows an inflammatory bowel disease pattern. Eradication of the parasite reverses these changes. In some patients with IgA deficiency, nodular lymphoid hyperplasia occurs, and this is usually not reversible. Other patients with hypogammaglobulinemia or dysgammaglobulinemia and giardiasis may show a sprue pattern. This pattern most often persists after eradication of the parasite. Although the triad of giardiasis, IgA deficiency, and nodular lymphoid hyperplasia has a particularly high association, these, together with diarrhea, malabsorption, and various altered immune states may occur in any combination.

摘要

蓝氏贾第鞭毛虫感染可导致严重腹泻和吸收不良,诊断通常通过粪便中囊肿的鉴定来进行,但可能需要进行小肠活检或涂片检查。可见广泛的X线改变。在免疫状态正常的患者中,小肠正常或呈现炎症性肠病模式。寄生虫的根除可逆转这些改变。在一些IgA缺乏的患者中,会出现结节性淋巴样增生,且这种情况通常不可逆。其他患有低丙种球蛋白血症或丙种球蛋白异常血症以及贾第虫病的患者可能呈现口炎性腹泻模式。这种模式在寄生虫根除后最常持续存在。尽管贾第虫病、IgA缺乏和结节性淋巴样增生三联征具有特别高的关联性,但这些情况与腹泻、吸收不良以及各种改变的免疫状态可能以任何组合形式出现。

相似文献

1
Current perspectives on giardiasis.贾第虫病的当前观点
Am J Roentgenol Radium Ther Nucl Med. 1975 Sep;125(1):207-17. doi: 10.2214/ajr.125.1.207.
2
Selective immunoglobulin A deficiency associated with modular lymphoid hyperplasia.与模块化淋巴组织增生相关的选择性免疫球蛋白A缺乏症。
J Allergy Clin Immunol. 1979 Dec;64(6 Pt 1):516-21. doi: 10.1016/0091-6749(79)90061-7.
3
[Nodular lymphoid hyperplasia of the small bowel with IgA deficiency and hemolytic anemia (author's transl)].伴有IgA缺乏和溶血性贫血的小肠结节性淋巴组织增生(作者译)
Med Clin (Barc). 1980 Oct 10;75(6):261-5.
4
Endoscopic visualization of nodular lymphoid hyperplasia.结节状淋巴样增生的内镜可视化。
Gastrointest Endosc. 1977 Aug;24(1):37-8. doi: 10.1016/s0016-5107(77)73439-x.
5
[Lymphoid hyperplasia of the intestine in children. 15 cases].[儿童肠道淋巴组织增生症。15例]
Ann Pediatr (Paris). 1992 Jun;39(6):359-64.
6
Nodular lymphoid hyperplasia of the small intestine and colon with giardiasis. A case with borderline serum IgA levels.小肠和结肠结节性淋巴组织增生合并贾第虫病。1例血清IgA水平临界的病例。
Am J Dig Dis. 1971 Aug;16(8):735-7. doi: 10.1007/BF02239601.
7
[Lymphoid hyperplasia in patients with diarrhea-manifestation of immunologic disturbances? (author's transl)].腹泻患者的淋巴样增生——免疫紊乱的表现?(作者译)
Leber Magen Darm. 1973 Feb;3(1):29-34.
8
The radiology corner: the small bowel in immunoglobulin deficiency syndromes.放射学专栏:免疫球蛋白缺乏综合征中的小肠
Am J Gastroenterol. 1975 Jul;64(1):59-73.
9
Immunodeficiency syndromes and gastrointestinal disease.免疫缺陷综合征与胃肠疾病。
Pediatr Clin North Am. 1975 Nov;22(4):807-25. doi: 10.1016/s0031-3955(16)33209-6.
10
[A case of hypogammaglobulinemia (IgA deficiency) with intestinal nodular lymphoid hyperplasia, bronchiectasis and recurrent diarrhea, with a special reference to the pathogenesis (author's transl)].
Nihon Naika Gakkai Zasshi. 1977 Mar 10;66(3):290-8. doi: 10.2169/naika.66.290.

引用本文的文献

1
IL-17A promotes protective IgA responses and expression of other potential effectors against the lumen-dwelling enteric parasite Giardia.白细胞介素-17A促进保护性免疫球蛋白A反应以及针对寄生于肠腔的肠道寄生虫贾第虫的其他潜在效应分子的表达。
Exp Parasitol. 2015 Sep;156:68-78. doi: 10.1016/j.exppara.2015.06.003. Epub 2015 Jun 9.
2
Mesenteric adenitis secondary to Giardia lamblia.贾第鞭毛虫继发的肠系膜腺炎
Dig Dis Sci. 1980 Dec;25(12):968-71. doi: 10.1007/BF01308049.
3
Progress report intestinal protozoa.肠道原生动物进展报告。
Gut. 1978 Oct;19(10):940-53. doi: 10.1136/gut.19.10.940.
4
Lymphoreticular disorders of the gastrointestinal tract: roentgenographic features.
Gastrointest Radiol. 1979 Apr 15;4(2):103-20. doi: 10.1007/BF01887508.
5
Immunoglobulin deficiency diseases of the intestine.
Gastrointest Radiol. 1977 Aug 18;2(1):7-11. doi: 10.1007/BF02256457.