Schroeder E B, Rosamond W D, Morris D L, Evenson K R, Hinn A R
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill 27599-8050, USA.
Stroke. 2000 Nov;31(11):2591-6. doi: 10.1161/01.str.31.11.2591.
With the advent of time-dependent thrombolytic therapy for ischemic stroke, it has become increasingly important for stroke patients to arrive at the hospital quickly. This study investigates the association between the use of emergency medical services (EMS) and delay time among individuals with stroke symptoms and examines the predictors of EMS use.
The Second Delay in Accessing Stroke Healthcare Study (DASH II) was a prospective study of 617 individuals arriving at emergency departments in Denver, Colo, Chapel Hill, NC, and Greenville, SC, with stroke symptoms.
EMS use was associated with decreased prehospital and in-hospital delay. Those who used EMS had a median prehospital delay time of 2.85 hours compared with 4.03 hours for those who did not use EMS (P:=0.002). Older individuals were more likely to use EMS (odds ratio [OR] 1.21 for each 5-year increase, 95% CI 1.14 to 1.29), as were individuals who expressed a high sense of urgency about their symptoms (OR 1.69, 95% CI 1.09 to 2.62). Knowledge of stroke symptoms was not associated with increased EMS use (OR 0.63, 95% CI 0.40 to 0.98). Patients were more likely to use EMS if someone other than the patient first identified that there was a problem (OR 2.35, 95% CI 1.61 to 3.44).
Interventions aimed at increasing EMS use among stroke patients need to stress the urgency of stroke symptoms and the importance of calling 911 and need to be broad-based, encompassing not only those at high risk for stroke but also their friends and family.
随着缺血性脑卒中时间依赖性溶栓治疗的出现,脑卒中患者快速抵达医院变得愈发重要。本研究调查了有卒中症状的个体使用紧急医疗服务(EMS)与延误时间之间的关联,并探讨了使用EMS的预测因素。
第二次卒中医疗救治延误研究(DASH II)是一项对617名有卒中症状并前往科罗拉多州丹佛市、北卡罗来纳州教堂山和南卡罗来纳州格林维尔市急诊科的个体进行的前瞻性研究。
使用EMS与院前及院内延误时间缩短相关。使用EMS的患者院前延误时间中位数为2.85小时,而未使用EMS的患者为4.03小时(P = 0.002)。年龄较大的个体更有可能使用EMS(每增加5岁优势比[OR]为1.21,95%置信区间为1.14至1.29),对自身症状表示高度紧迫感的个体也是如此(OR为1.69,95%置信区间为1.09至2.62)。对卒中症状的了解与增加EMS使用无关(OR为0.63,95%置信区间为0.40至0.98)。如果不是患者本人首先发现问题,患者更有可能使用EMS(OR为2.35,95%置信区间为1.61至3.44)。
旨在增加卒中患者使用EMS的干预措施需要强调卒中症状的紧迫性以及拨打911的重要性,并且需要具有广泛基础,不仅涵盖卒中高危人群,还包括他们的朋友和家人。