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局限性前列腺癌治疗后的尿失禁

Urinary incontinence after treatment for localized prostate cancer.

作者信息

Krane R J

机构信息

Department of Urology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

出版信息

Mol Urol. 2000 Fall;4(3):279-86;discussion 287.

PMID:11062385
Abstract

The incidence of incontinence after radical prostatectomy has ranged from 0 to 57% depending on the series and the type of incontinence considered. When total incontinence (not minimal stress incontinence) is reported, the average incidence is no more than 5%. This figure will increase with age, and in most series, approximately 10% of patients around the age of 70 will have total incontinence postoperatively. Preservation of continence after radical prostatectomy depends largely on the preservation of the distal urethral smooth-muscle sphincteric mechanism, which begins at the pelvic floor and ends at the prostatourethral junction. Newer techniques that attempt to increase postoperative continence include not cutting the puboprostatic ligaments and attempting to preserve as much striated muscle as possible along the length of the remaining urethra. Patients who are incontinent for 6 months after the surgery with no evidence of improvement will probably not become continent on their own. Therefore, some type of therapy should be considered. The options are periurethral injection of a bulking agent, implantation of an artificial sphincter, and, most recently, a bulbourethral sling procedure.

摘要

根据不同的研究系列以及所考虑的尿失禁类型,根治性前列腺切除术后尿失禁的发生率在0%至57%之间。当报告的是完全性尿失禁(而非轻度压力性尿失禁)时,平均发生率不超过5%。这一数字会随着年龄增长而增加,在大多数研究系列中,70岁左右的患者中约有10%术后会出现完全性尿失禁。根治性前列腺切除术后控尿情况很大程度上取决于远端尿道平滑肌括约肌机制的保留,该机制始于盆底,止于前列腺尿道交界处。试图提高术后控尿能力的新技术包括不切断耻骨前列腺韧带,并尽可能保留剩余尿道长度上的横纹肌。术后6个月仍有尿失禁且无改善迹象的患者可能无法自行恢复控尿。因此,应考虑某种类型的治疗。治疗选择包括尿道周围注射填充剂、植入人工括约肌,以及最近出现的球尿道悬吊手术。

相似文献

1
Urinary incontinence after treatment for localized prostate cancer.局限性前列腺癌治疗后的尿失禁
Mol Urol. 2000 Fall;4(3):279-86;discussion 287.
2
[Urodynamics of urinary incontinence post radical prostatectomy].[根治性前列腺切除术后尿失禁的尿动力学研究]
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Bulbourethral composite suspension:: a new operative technique for post-prostatectomy incontinence.球部尿道复合悬吊术:一种前列腺切除术后尿失禁的新手术技术。
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The role of membranous urethral afferent autonomic innervation in the continence mechanism after nerve sparing radical prostatectomy: a clinical and prospective study.保留神经的根治性前列腺切除术后膜性尿道传入自主神经支配在控尿机制中的作用:一项临床前瞻性研究。
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Inefficient urethral milking secondary to urethral dysfunction as an additional risk factor for incontinence after radical prostatectomy.由于尿道功能障碍导致的无效尿道按摩是前列腺癌根治术后尿失禁的另一个风险因素。
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Changes in continence and erectile function between 2 and 4 years after radical prostatectomy.前列腺癌根治术后2至4年间尿失禁和勃起功能的变化。
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Five-year outcomes after prostatectomy or radiotherapy for prostate cancer: the prostate cancer outcomes study.前列腺癌前列腺切除术后或放疗后的五年预后:前列腺癌预后研究
J Natl Cancer Inst. 2004 Sep 15;96(18):1358-67. doi: 10.1093/jnci/djh259.

引用本文的文献

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Patient Reported Outcomes and Treatment-Associated Complications as a Consideration in Selecting Localized Prostate Cancer Management.患者报告的结局和治疗相关并发症作为选择局限性前列腺癌治疗方案时的考虑因素。
Res Rep Urol. 2025 Jun 12;17:195-210. doi: 10.2147/RRU.S386383. eCollection 2025.
2
Sonic hedgehog regulation of human rhabdosphincter muscle:Potential implications for treatment of stress urinary incontinence.超声 Hedgehog 对人横纹括约肌的调节:治疗压力性尿失禁的潜在意义。
Neurourol Urodyn. 2018 Nov;37(8):2551-2559. doi: 10.1002/nau.23813. Epub 2018 Sep 6.
3
The Role of Urodynamics in Post-Prostatectomy Incontinence.
尿动力学在前列腺切除术后尿失禁中的作用。
Curr Urol Rep. 2018 Feb 26;19(3):21. doi: 10.1007/s11934-018-0770-7.