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[根治性前列腺切除术后尿失禁的尿动力学研究]

[Urodynamics of urinary incontinence post radical prostatectomy].

作者信息

Salinas Casado J, Virseda Chamorro M, Fernández Ajubita H, Ramírez Fernández J C, Fuentes Márquez I, Resel Estévez L

机构信息

Servicio de Urología, Hospital Universitario San Carlos, Universidad Complutense, Madrid, España.

出版信息

Arch Esp Urol. 1998 Oct;51(8):801-10.

PMID:9859586
Abstract

OBJECTIVE

To determine the urodynamic characteristics of urinary incontinence after radical retropubic prostatectomy.

METHODS

We conducted a clinical and urodynamic study on 25 patients who had undergone radical retropubic prostatectomy due to localized prostate adenocarcinoma.

RESULTS

68% of the patients completely recovered urinary continence. The maximum rate of urinary continence recovery was found between the third and fourth month postprostatectomy. A relationship was demonstrated between preoperative hormone blockade, duration of the surgery and urinary continence. Videocystography demonstrated an incompetent proximal continence mechanism in all radical prostatectomy patients. All incontinent patients presented stress urinary incontinence. Denervation potentials of the periurethral sphincter was demonstrated by electromyography in 80% of incontinent patients. These potentials were not present in the continent patients. Reinnervation potentials were present in 50% of the continent patients and in 20% of the incontinent patients (significant differences). No relationship was found between other urodynamic data and post-radical prostatectomy urinary incontinence.

CONCLUSIONS

The surgical difficulty influences the preservation of urinary continence. A high percentage of patients submitted to radical prostatectomy recover urinary continence with time. Urinary incontinence following radical prostatectomy is based on the distal sphincteric mechanism. Patients who remain incontinent four months postoperatively and with electromyographically demonstrated denervation potentials of the periurethral sphincter can be considered to be candidates for treatment of incontinence without waiting any further.

摘要

目的

确定耻骨后根治性前列腺切除术后尿失禁的尿动力学特征。

方法

我们对25例因局限性前列腺腺癌接受耻骨后根治性前列腺切除术的患者进行了临床和尿动力学研究。

结果

68%的患者完全恢复了控尿功能。前列腺切除术后第3至4个月时控尿恢复率最高。术前激素阻断、手术持续时间与控尿之间存在关联。膀胱造影显示所有根治性前列腺切除术患者近端控尿机制功能不全。所有失禁患者均表现为压力性尿失禁。80%的失禁患者经肌电图检查显示尿道周围括约肌失神经电位。控尿患者中不存在这些电位。50%的控尿患者和20%的失禁患者存在再支配电位(差异有统计学意义)。未发现其他尿动力学数据与根治性前列腺切除术后尿失禁之间存在关联。

结论

手术难度影响控尿功能的保留。接受根治性前列腺切除术的患者中有很大比例会随着时间的推移恢复控尿功能。根治性前列腺切除术后的尿失禁基于远端括约肌机制。术后4个月仍失禁且经肌电图证实尿道周围括约肌失神经电位的患者可被视为失禁治疗的候选者,无需再等待。

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[Urodynamics of urinary incontinence post radical prostatectomy].[根治性前列腺切除术后尿失禁的尿动力学研究]
Arch Esp Urol. 1998 Oct;51(8):801-10.
2
Urinary incontinence and voiding dysfunction after radical retropubic prostatectomy (prospective urodynamic study).耻骨后根治性前列腺切除术后的尿失禁和排尿功能障碍(前瞻性尿动力学研究)
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[Radical prostatectomy: usefulness of selective electromyography of the periurethral sphincter in the assessment of urinary continence].
Arch Esp Urol. 1994 Jun;47(5):483-7.
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Effect of radical prostatectomy on sensory threshold and pressure transmission.根治性前列腺切除术对感觉阈值和压力传导的影响。
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[Clinical and neuro-urodynamic assessment of radical prostatectomy].[根治性前列腺切除术的临床及神经尿动力学评估]
Arch Esp Urol. 1996 Mar;49(2):125-31.
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The etiology of post-radical prostatectomy incontinence and correlation of symptoms with urodynamic findings.根治性前列腺切除术后尿失禁的病因及症状与尿动力学检查结果的相关性。
J Urol. 1998 Oct;160(4):1317-20.
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Urethral pressure profile 6 months after radical prostatectomy may be diagnostic of sphincteric incontinence: preliminary data after 12 months' follow-up.根治性前列腺切除术后6个月的尿道压力分布图可能有助于诊断括约肌性尿失禁:12个月随访后的初步数据。
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Urodynamic evaluation of a suspension technique for rapid recovery of continence after radical retropubic prostatectomy.耻骨后根治性前列腺切除术后采用一种悬吊技术实现快速控尿的尿动力学评估。
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Do clinical or urodynamic parameters predict artificial urinary sphincter outcome in post-radical prostatectomy incontinence?临床或尿动力学参数能否预测根治性前列腺切除术后尿失禁患者人工尿道括约肌的治疗效果?
Urology. 2007 Feb;69(2):315-9. doi: 10.1016/j.urology.2006.10.026.

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