Salinas Casado J, Virseda Chamorro M, Fernández Ajubita H, Ramírez Fernández J C, Fuentes Márquez I, Resel Estévez L
Servicio de Urología, Hospital Universitario San Carlos, Universidad Complutense, Madrid, España.
Arch Esp Urol. 1998 Oct;51(8):801-10.
To determine the urodynamic characteristics of urinary incontinence after radical retropubic prostatectomy.
We conducted a clinical and urodynamic study on 25 patients who had undergone radical retropubic prostatectomy due to localized prostate adenocarcinoma.
68% of the patients completely recovered urinary continence. The maximum rate of urinary continence recovery was found between the third and fourth month postprostatectomy. A relationship was demonstrated between preoperative hormone blockade, duration of the surgery and urinary continence. Videocystography demonstrated an incompetent proximal continence mechanism in all radical prostatectomy patients. All incontinent patients presented stress urinary incontinence. Denervation potentials of the periurethral sphincter was demonstrated by electromyography in 80% of incontinent patients. These potentials were not present in the continent patients. Reinnervation potentials were present in 50% of the continent patients and in 20% of the incontinent patients (significant differences). No relationship was found between other urodynamic data and post-radical prostatectomy urinary incontinence.
The surgical difficulty influences the preservation of urinary continence. A high percentage of patients submitted to radical prostatectomy recover urinary continence with time. Urinary incontinence following radical prostatectomy is based on the distal sphincteric mechanism. Patients who remain incontinent four months postoperatively and with electromyographically demonstrated denervation potentials of the periurethral sphincter can be considered to be candidates for treatment of incontinence without waiting any further.
确定耻骨后根治性前列腺切除术后尿失禁的尿动力学特征。
我们对25例因局限性前列腺腺癌接受耻骨后根治性前列腺切除术的患者进行了临床和尿动力学研究。
68%的患者完全恢复了控尿功能。前列腺切除术后第3至4个月时控尿恢复率最高。术前激素阻断、手术持续时间与控尿之间存在关联。膀胱造影显示所有根治性前列腺切除术患者近端控尿机制功能不全。所有失禁患者均表现为压力性尿失禁。80%的失禁患者经肌电图检查显示尿道周围括约肌失神经电位。控尿患者中不存在这些电位。50%的控尿患者和20%的失禁患者存在再支配电位(差异有统计学意义)。未发现其他尿动力学数据与根治性前列腺切除术后尿失禁之间存在关联。
手术难度影响控尿功能的保留。接受根治性前列腺切除术的患者中有很大比例会随着时间的推移恢复控尿功能。根治性前列腺切除术后的尿失禁基于远端括约肌机制。术后4个月仍失禁且经肌电图证实尿道周围括约肌失神经电位的患者可被视为失禁治疗的候选者,无需再等待。