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双盲研究中盐酸芬地林长期治疗后的冠状侧支血管(作者译)

[Coronary collateral vessels after long-term treatment with fendiline hydrochloride in a double-blind study (author's transl)].

作者信息

Knoche H, Schmitt G

出版信息

Arzneimittelforschung. 1975 Nov;25(11):1781-2.

PMID:1106442
Abstract

After long-therapy with 5 mg/kg body-weight of N-(2-benzhydryl-ethyl)-N-(1-phenyl-ethyl)amine hydrochloride (fendiline hydrochloride, Sensit) in dogs the development of functioning coronary collateral vessels can be proven by filling the vessel system with synthetic resin. From earlier studies, it is known that coronary collateral vessels can protect the heart from the consequences of stenoses and tissue damage due to hypoxia.

摘要

在犬类中,以5毫克/千克体重的N-(2-二苯甲基-乙基)-N-(1-苯基-乙基)胺盐酸盐(盐酸芬地林,Sensit)进行长期治疗后,通过向血管系统注入合成树脂可证实功能性冠状动脉侧支血管的形成。从早期研究可知,冠状动脉侧支血管可保护心脏免受狭窄及缺氧所致组织损伤的影响。

相似文献

1
[Coronary collateral vessels after long-term treatment with fendiline hydrochloride in a double-blind study (author's transl)].双盲研究中盐酸芬地林长期治疗后的冠状侧支血管(作者译)
Arzneimittelforschung. 1975 Nov;25(11):1781-2.
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