Rocha A, Miguel O F, Barbosa H M, Candelori I, da Silva A M, Lopes E R
Serviço de Anatomia Patológica, Hospital de Clínicas da Universidade Federal de Uberiândia, MG, Brasil.
Rev Soc Bras Med Trop. 2000 Sep-Oct;33(5):413-6.
The occurrence of Trypanosoma cruzi intracellular clusters and phlebitis was searched for on pampiniform plexus vein walls of chronic chagasic patients. For this purpose, 23 pairs of spermatic cords, epididymides and testes (17 from chagasic patients and 6 from non-chagasic controls) were obtained, at autopsy. Trypanosoma cruzi was investigated by immuno-histochemistry on slides obtained from several sections of the gonads and vessels of each case. Only discrete and focal undetermined chronic phlebitis was observed, with no parasites, in 5 chagasics (bilateral in 3) and 2 controls (chi 2: p < 0.10), and discrete mononuclear interstitial infiltration in the funiculi of 13 chagasics and 5 controls (chi 2: p < 0.75). In conclusion, on the contrary to that published regarding the supra-renal central veins, it seems that the hormonal environment provided by testosterone does not favor the infection of the gonadal vessel wall.
在慢性恰加斯病患者的蔓状静脉丛静脉壁上寻找克氏锥虫细胞内簇和静脉炎的发生情况。为此，在尸检时获取了23对精索、附睾和睾丸（17对来自恰加斯病患者，6对来自非恰加斯病对照）。通过免疫组织化学对从每个病例的性腺和血管的多个切片获得的载玻片上的克氏锥虫进行研究。仅在5名恰加斯病患者（3例双侧）和2名对照中观察到离散的局灶性未确定的慢性静脉炎，无寄生虫（卡方检验：p < 0.10），在13名恰加斯病患者和5名对照的精索中有离散的单核间质浸润（卡方检验：p < 0.75）。总之，与关于肾上腺中央静脉的已发表内容相反，睾酮提供的激素环境似乎并不利于性腺血管壁的感染。
