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实验性恰加斯病慢性期的男性生殖器官

The male reproductive organs in the chronic phase of experimental Chagas' disease.

作者信息

Carraro A A, Lopes R A, Ribeiro R D, Lamano Carvalho T L

机构信息

Laboratory of Parasitology, Faculty of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Brasil.

出版信息

Angew Parasitol. 1992 Feb;33(1):3-9.

PMID:1590593
Abstract

A previous study showed amastigote forms of Trypanosoma cruzi in the sex organs of male mice 15 days after inoculation. The purpose of the present work was to investigate the sequelae occurring in the male reproductive system during a later phase of Chagas' disease. Depleted germinal epithelium and release of immature germ cells into the tubular lumen were observed in the testis of chronic chagasic mice. The relative weights of the epididymis, vas deferens and seminal vesicle were significantly increased. Histological examination revealed a sharp thinning of the ductal and acinar walls. The results are discussed in terms of a neuromotor disturbance leading to sperm retention.

摘要

先前的一项研究显示,接种后15天,雄性小鼠的性器官中出现了克氏锥虫的无鞭毛体形式。本研究的目的是调查恰加斯病后期男性生殖系统中出现的后遗症。在慢性恰加斯病小鼠的睾丸中观察到生精上皮耗竭以及未成熟生殖细胞释放到管腔中。附睾、输精管和精囊的相对重量显著增加。组织学检查显示导管和腺泡壁明显变薄。从导致精子潴留的神经运动障碍方面对结果进行了讨论。

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