Wali Y A, Venugopalan P, Rivera E, al-Lamki Z
Department of Child Health, College of Medicine, Sultan Qaboos University, Muscat, Oman.
Ann Trop Paediatr. 2000 Sep;20(3):243-6. doi: 10.1080/02724936.2000.11748143.
Systolic murmurs were detected in 22 (61%) of the 36 children with sickle cell anaemia (SCA) who completed the study. Cardiomegaly was detected in 14 (39%). Mean values of left and right ventricular dimensions were higher in SCA than in controls (p < 0.05). Left atrial chambers and aortic root dimensions followed the same pattern. The dilated cardiac chambers in SCA were not associated with any abnormality in systolic or diastolic left ventricular function nor with significant pulmonary hypertension.
在完成该研究的36例镰状细胞贫血（SCA）患儿中，22例（61%）检测到收缩期杂音。14例（39%）检测到心脏扩大。SCA患儿左、右心室尺寸的平均值高于对照组（p<0.05）。左心房和主动脉根部尺寸也呈现相同模式。SCA中扩张的心脏腔室与左心室收缩或舒张功能的任何异常均无关联，也与显著的肺动脉高压无关。
