Cosgrove D J, Monga M
Division of Urology, University of California, San Diego, Medical Center, San Diego, California, USA.
Urology. 2000 Nov 1;56(5):856. doi: 10.1016/s0090-4295(00)00787-1.
Inverted papilloma of the urinary tract is a rare benign lesion. We report, to our knowledge, the first case of high-grade ureteral obstruction caused by an inverted papilloma with coexistent carcinomatous elements. Our patient was referred for evaluation of painless, gross hematuria. Imaging studies demonstrated a left proximal ureteral filling defect causing severe left-sided hydroureteronephrosis. Ureteroscopy demonstrated a 1-cm papillary lesion on the medial aspect of the proximal ureteral wall. Pathologic examination documented a lesion with elements of inverted papilloma and a small focus of well-differentiated transitional cell carcinoma. We discuss the management and significance of this rare urothelial lesion.
尿路内翻性乳头状瘤是一种罕见的良性病变。据我们所知，我们报告了首例由伴有癌性成分的内翻性乳头状瘤引起的重度输尿管梗阻病例。我们的患者因无痛性肉眼血尿前来接受评估。影像学检查显示左近端输尿管充盈缺损，导致严重的左侧肾盂积水和输尿管积水。输尿管镜检查发现近端输尿管壁内侧有一个1厘米的乳头状病变。病理检查证实该病变具有内翻性乳头状瘤成分以及一个小灶性高分化移行细胞癌。我们讨论了这种罕见的尿路上皮病变的处理方法及意义。
