Sasaki Y, Yamagishi F, Yagi T, Yamatani H, Kuroda F, Shoda H
Division of Thoracic Disease, National Chiba Higashi Hospital, Japan.
Kekkaku. 2000 Sep;75(9):527-32.
Epidemiological trend of tuberculosis in Japan has reversed recently. The incidence of pulmonary tuberculosis (PTB) patients has increased again in Japan, and many outbreaks of PTB including nosocomial outbreaks in health-care facilities have been reported. The purpose of this study is to investigate patient's delay (interval between onset of the disease and first visit to a doctor) and doctor's delay (interval between first visit to a doctor and diagnosis as TB) in patients with PTB discovered by visiting doctors with symptoms, and especially, to investigate causes of doctor's delay in details. Of 236 PTB patients who were admitted to our hospital for treatment in 1997, 118 patients (85 males, 33 females) who were detected by their symptomatic visits were enrolled in to this study. 97 were initial treatment cases and the others were re-treatment cases. Among 34 initial treatment cases who were first seen at a general hospital and diagnosed as PTB by a close medical checkup after admission to our hospital, the 50 percentile of patient's delay was 17.0 days, and the 80 percentile was 36.4 days. The 50 percentile doctor's delay was 19.6 days, and the 80 percentile was 64.2 days. The average hospital stay was 16.2 days, the 50 percentile hospital stay was 7.8 days, and 80 percentile hospital stay was 23.5 days. On the sputum test for acid fast bacilli (AFB) performed on admission to our hospital, 26(76%) out of 34 cases were positive for tubercle bacilli, with 18 cases were positive for smear and 8 cases positive for culture. Therefore, risk of nosocomial infection was suspected. Doctor's delay had been attributed mainly to insufficient medical checkup. Among 25 initial treatment cases in whom doctor's delay as more than 4 weeks, 11 cases (44%) showed delay in chest X-ray examination and 8 cases (32%) ordered no sputum examination in spite of recognition of abnormal shadows on chest X-ray. On the sputum test for AFB on admission to our hospital, 22 (88%) out of 25 cases were positive for tubercle bacilli. Therefore, it is assumed that the delay in the adequate medical checkup was accountable for the doctor's delay. Shortening of the doctor's delay could be possible if hospitals perform the sputum examination for AFB and chest X-ray examinations properly for patients with respiratory symptoms.
日本结核病的流行病学趋势最近出现了逆转。日本肺结核(PTB)患者的发病率再次上升,并且已经报告了许多PTB疫情,包括医疗机构内的医院感染爆发。本研究的目的是调查有症状就诊的医生发现的PTB患者的患者延迟(疾病发作与首次就诊医生之间的间隔)和医生延迟(首次就诊医生与诊断为结核病之间的间隔),特别是详细调查医生延迟的原因。1997年在我院住院治疗的236例PTB患者中,118例(85例男性,33例女性)因有症状就诊被检测出而纳入本研究。97例为初治病例,其余为复治病例。在34例初治病例中,这些病例最初在综合医院就诊,入院后经仔细体检被诊断为PTB,患者延迟的第50百分位数为17.0天,第80百分位数为36.4天。医生延迟的第50百分位数为19.6天,第80百分位数为64.2天。平均住院天数为16.2天,住院天数的第50百分位数为7.8天,第80百分位数为23.5天。在我院入院时进行的痰涂片抗酸杆菌(AFB)检测中,34例中有26例(76%)结核杆菌呈阳性,其中18例涂片阳性,8例培养阳性。因此,怀疑存在医院感染风险。医生延迟主要归因于体检不足。在25例医生延迟超过4周的初治病例中,11例(44%)胸部X线检查延迟,8例(32%)尽管胸部X线检查发现异常阴影但未进行痰检。在我院入院时进行的痰涂片AFB检测中,25例中有22例(88%)结核杆菌呈阳性。因此,可以认为适当体检的延迟是医生延迟的原因。如果医院对有呼吸道症状的患者正确进行痰涂片AFB检查和胸部X线检查,医生延迟有可能缩短。