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[晚期空洞型肺结核病例研究]

[A study on far-advanced cavitary pulmonary tuberculosis cases].

作者信息

Sasaki Yuka, Yamagishi Fumio, Yagi Takenori, Yamatani Hideki, Kuroda Fuminobu, Shoda Hideaki

机构信息

Division of Thoracic Disease, National Chiba Higashi Hospital, 673, Nitona-cho, Chuo-ku, Chiba-shi, Chiba 260-8712, Japan.

出版信息

Kekkaku. 2002 Jun;77(6):443-8.

Abstract

In cases with far-advanced cavitary pulmonary tuberculosis, the most serious lesions according to the chest X-ray classification by the Japanese Society of Tuberculosis (b I 3), their prognosis is believed to be poor due to their emaciated general conditions, and a retrospective clinical study was made on these cases admitted to our hospital. The subjects consisted of 95 cases, and among them 87 were male and 8 were female, and their mean age was 49.5 +/- 13.0 years. Eighty four cases were detected by symptomatic visits to clinics, 10 cases during their treatment for other diseases, and 1 case was discovered accidentally. Sputum examination for acid fast bacilli was all smear positive. As to their social background, the majority were occupied by socially vulnerable groups; 31 cases (32.6%) were jobless on admission, 24 cases (25.3%) were day laborers, and 25 cases (26.3%) were receiving poor relief. Regarding their general condition on admission, 40 cases were very serious and they could not stand by themselves, and their nutritional conditions were poor, and 19 cases (20%) died during hospitalization. All of them were male, and they were found by symptomatic visit to clinics. The period from hospital admission to death was short, the average was 35.0 +/- 39.8 days, and the median was 11.0 days. Among 84 patients detected by symptomatic visit, the patient's delay was 5.5 +/- 5.0 months, while the doctor's delay was 0.3 +/- 0.9 months. Major cause of late detection at advanced stage of these cases was patient's delay which caused poor prognosis of these cases, and various measures to shorten the delay in case-detection must be taken.

摘要

在晚期空洞型肺结核病例中,根据日本结核病学会的胸部X线分类(b I 3),这些是最严重的病变,由于其全身状况消瘦,预后被认为很差,因此对我院收治的这些病例进行了回顾性临床研究。研究对象包括95例患者,其中男性87例,女性8例,平均年龄为49.5±13.0岁。84例通过临床症状就诊发现,10例在治疗其他疾病期间发现,1例偶然发现。痰涂片抗酸杆菌检查均为阳性。就其社会背景而言,大多数为社会弱势群体;31例(32.6%)入院时无业,24例(25.3%)为临时工,25例(26.3%)领取贫困救济。入院时其全身状况方面,40例非常严重,无法自理,营养状况较差,19例(20%)在住院期间死亡。所有死亡患者均为男性,通过临床症状就诊发现。从入院到死亡的时间较短,平均为35.0±39.8天,中位数为11.0天。在84例通过临床症状就诊发现的患者中,患者延迟就诊时间为5.5±5.0个月,而医生延迟诊断时间为0.3±0.9个月。这些病例晚期发现的主要原因是患者延迟就诊,导致预后不良,必须采取各种措施缩短病例发现的延迟时间。

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