Sharifah N A, Muhaizan W M, Rahman J, Zulfikar A, Zahari Z
Department of Pathology, Universiti Kebangsaan Malaysia.
Malays J Pathol. 1999 Dec;21(2):105-9.
The cytological features of a rare case of undifferentiated (embryonal) sarcoma of the liver are presented. The cytology smears showed singly dispersed polygonal and spindle cells as well as loose clusters of cells held together in myxoid material. Neoplastic cells were generally large with round, oval or lobulated nuclei. The cytoplasm was variable in amount with ill-defined borders. Occasional multinucleated cells were also present. Hyaline globules were present on sections of the cell block. Immunohistochemical studies performed showed positivity for vimentin, cytokeratin and alpha-1-antitrypsin (AAT) in the tumour cells.
本文呈现了一例罕见的肝脏未分化(胚胎性)肉瘤的细胞学特征。细胞学涂片显示有单个散在的多边形和梭形细胞,以及在黏液样物质中聚集在一起的松散细胞团。肿瘤细胞通常较大,核呈圆形、椭圆形或分叶状。细胞质数量不一,边界不清。偶尔也可见多核细胞。细胞块切片上有透明小球。进行的免疫组织化学研究显示肿瘤细胞中波形蛋白、细胞角蛋白和α-1-抗胰蛋白酶(AAT)呈阳性。