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[鉴别引起帕金森综合征的各种疾病的要点]

[Essential points to differentiate various diseases causing parkinsonism].

作者信息

Kuzuhara S

机构信息

Department of Neurology, Mie University School of Medicine.

出版信息

Nihon Rinsho. 2000 Oct;58(10):2049-53.

PMID:11068445
Abstract

This review article deals with the cardinal features to differentiate various conditions which present with parkinsonism, other than Parkinson's disease, Lewy body disease, progressive supranuclear palsy and corticobasal degeneration. Special attention is paid to the distinctive clinical features, laboratory data and neuroimaging findings of frequent diseases as well as important ones including multiple system atrophies(MSA), drug-induced parkinsonism, vascular pseudo-parkinsonism and manganese intoxication due to parenteral nutrition. MRI is useful to diagnose MSA, vascular pseudo-parkinsonism and manganese intoxication. Benzamide derivatives including sulpiride, tiapride, metoclopramide and cisapride are the main causes of drug-induced parkinsonism in recent years in Japan.

摘要

这篇综述文章探讨了除帕金森病、路易体病、进行性核上性麻痹和皮质基底节变性外,鉴别各种帕金森综合征的主要特征。特别关注常见疾病以及包括多系统萎缩(MSA)、药物性帕金森综合征、血管性假性帕金森综合征和肠外营养所致锰中毒等重要疾病的独特临床特征、实验室数据和神经影像学表现。MRI有助于诊断MSA、血管性假性帕金森综合征和锰中毒。在日本,近年来包括舒必利、硫必利、甲氧氯普胺和西沙必利在内的苯甲酰胺衍生物是药物性帕金森综合征的主要病因。

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