Tison F
Département de Neurologie, Hôpital Pellegrin, Bordeaux, France.
Baillieres Clin Neurol. 1997 Apr;6(1):205-18.
This chapter deals with the 'other causes of parkinsonism with the exclusion of idiopathic Parkinson's disease, multiple system atrophy, progressive supranuclear palsy and corticobasal degeneration. It is a cursory glance over the endless list of 'secondary' causes of parkinsonism or parkinsonism due to acquired and inherited metabolic and neurodegenerative diseases. With the exception of drug-induced parkinsonism and 'vascular' parkinsonism, most such cases are rare. However, single rare causes must not be overlooked as there can be specific therapeutic consequences. Parkinsonism is often present amid a constellation of other symptoms. Careful evaluation of the personal, familial and environmental context, mode of onset and progression, clinical features, and drug response, together with imaging, biochemical and molecular tests, help in determining the underlying disease.
本章论述帕金森综合征的“其他病因”，不包括特发性帕金森病、多系统萎缩、进行性核上性麻痹和皮质基底节变性。这是对帕金森综合征“继发性”病因或由获得性及遗传性代谢和神经退行性疾病导致的帕金森综合征这一无尽列表的粗略审视。除药物性帕金森综合征和“血管性”帕金森综合征外，大多数此类病例都很罕见。然而，单个罕见病因不可忽视，因为可能会有特定的治疗后果。帕金森综合征常与一系列其他症状同时出现。仔细评估个人、家族和环境背景、起病方式和进展、临床特征、药物反应，以及影像学、生化和分子检测，有助于确定潜在疾病。
