Bohotin C, Leca V, Luca V, Costuleanu M, Vornicu M, Bohotin V, Bădescu M
Department of Pathophysiology, University of Medicine and Pharmacy, Iaşi, Romania.
Rom J Physiol. 1999 Jan-Jun;36(1-2):3-9.
In order to evaluate the effect of the acute viral hepatitis on arterial blood flow we performed duplex Doppler US on 30 patients with acute viral hepatitis (AVH) and compared the results with those obtained on 20 normal volunteers. Hepatic artery flow (HAF) was significantly increased with the patients suffering from acute viral hepatitis. The data obtained show that the increase of arterial blood flow is not always associated with the increase of arterial velocities. We could put in evidence the presence of the hepatic artery response to altered portal blood flow (arterial buffer) during a AVH. If the increase of HAF is absolutely necessary for recovery from hepatitis, excessive increase of HAF seems to increase the time of recovery. In our study, the evolution of acute viral hepatitis was good when the HAF values did not exceed 65% of liver supply. The increase of arterial blood flow over 65% seems to limit the portal supply of the liver and in this way the amounts of regenerating substances which bathe the liver cells. The HAF value plays an important role in acute viral hepatitis evolution, so that the exploration of HAF and hepatic artery velocities may be a reliable examination in order to monitor the evolution of this disease.
为了评估急性病毒性肝炎对动脉血流的影响，我们对30例急性病毒性肝炎（AVH）患者进行了双功多普勒超声检查，并将结果与20名正常志愿者的结果进行了比较。急性病毒性肝炎患者的肝动脉血流（HAF）显著增加。所获得的数据表明，动脉血流的增加并不总是与动脉速度的增加相关。我们可以证明在急性病毒性肝炎期间肝动脉对门静脉血流改变（动脉缓冲）的反应存在。如果HAF的增加对肝炎恢复绝对必要，那么HAF的过度增加似乎会延长恢复时间。在我们的研究中，当HAF值不超过肝脏供血的65%时，急性病毒性肝炎的病情发展良好。动脉血流增加超过65%似乎会限制肝脏的门静脉供血，从而减少流经肝细胞的再生物质数量。HAF值在急性病毒性肝炎的病情发展中起着重要作用，因此，检测HAF和肝动脉速度可能是监测该疾病病情发展的一项可靠检查。
