Rutter G A
Department of Biochemistry, School of Medical Sciences, University of Bristol, UK.
Curr Biol. 2000 Oct 19;10(20):R736-8. doi: 10.1016/s0960-9822(00)00737-5.
Insulin resistance, the hallmark of non-insulin dependent diabetes mellitus, is characterized by the failure of tissues to take up and store glucose in response to insulin. Two recent studies shed new light on the importance of insulin signalling in the liver and how this may become defective in diabetes.
胰岛素抵抗是非胰岛素依赖型糖尿病的标志，其特征是组织无法响应胰岛素摄取和储存葡萄糖。最近的两项研究为肝脏中胰岛素信号传导的重要性以及糖尿病中该信号传导可能如何出现缺陷提供了新的线索。
