Bastl C P, Hendler E D, Finkelstein F O
Clin Nephrol. 1975 Dec;4(6):228-33.
A retrospective study of the response of the leukocyte count to renal transplant rejection was performed in 159 rejection episodes. Results of the study showed that 1. contrary to what is commonly thought leukocytosis is the least common response to acute rejection and a decrease in leukocyte count is far more common, 2. a sudden decrease in leukocyte count in a previously stable patient can be an early sign of rejection, 3. there is a significantly greater incidence of graft loss in rejection episodes characterized by leukopenia and 4. the risk of infection following rejection is greatest in patients with rejection characterized by leukopenia.
对159次肾移植排斥反应中白细胞计数的反应进行了一项回顾性研究。研究结果表明：1. 与通常的看法相反，白细胞增多是急性排斥反应最不常见的反应，白细胞计数下降更为常见；2. 先前病情稳定的患者白细胞计数突然下降可能是排斥反应的早期迹象；3. 以白细胞减少为特征的排斥反应中移植物丢失的发生率显著更高；4. 以白细胞减少为特征的排斥反应患者排斥反应后感染风险最大。
