Daar A S, Morris P J, Oliver D O
Br Med J. 1977 Dec 17;2(6102):1570-1. doi: 10.1136/bmj.2.6102.1570.
The leucocyte response to allograft rejection was retrospectively analysed in 80 rejection episodes that occurred in 50 patients. There was no significant change in leucocyte count in 32 rejection episodes. In 27 there was a fall in leucocyte count of more than 20% and in only 21 was there a rise in count of more than 20%. Thus leucocytosis seems not to be a manifestation of rejection; indeed, it is the least common response, a fall in the count being commoner. The results also suggest that the prognosis for the graft is poorer when the leucocyte count falls significantly.
对50例患者发生的80次排斥反应进行了回顾性分析,观察白细胞对同种异体移植排斥反应的情况。32次排斥反应中白细胞计数无显著变化。27次排斥反应中白细胞计数下降超过20%,只有21次白细胞计数上升超过20%。因此,白细胞增多似乎不是排斥反应的表现;事实上,它是最不常见的反应,白细胞计数下降更为常见。结果还表明,当白细胞计数显著下降时,移植预后较差。