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用于颈动脉内膜切除术的异氟烷、地氟烷和七氟烷。

Isoflurane, desflurane and sevoflurane for carotid endarterectomy.

作者信息

Umbrain V, Keeris J, D'Haese J, Verborgh C, Debing E, Van den Brande P, Camu F

机构信息

Department of Anaesthesia, Akademisch Ziekenhuis, Vrije Universiteit Brussel, Brussels, Belgium,

出版信息

Anaesthesia. 2000 Nov;55(11):1052-7. doi: 10.1046/j.1365-2044.2000.01617.x.

DOI:10.1046/j.1365-2044.2000.01617.x
PMID:11069330
Abstract

After carotid endarterectomy under general anaesthesia, the rapid elimination of desflurane and sevoflurane may allow earlier postoperative neurological assessment than after the use of isoflurane. However, desflurane may be associated with tachycardia and hypertension and may therefore increase cardiovascular risk. We investigated haemodynamic and recovery characteristics in patients scheduled for carotid endarterectomy who were anaesthetised with isoflurane, sevoflurane or desflurane. No significant peri-operative differences were noted in cardiac index or ST segment analysis. The times to extubation, movement on command and consciousness were shorter after desflurane and sevoflurane than after isoflurane anaesthesia. Postoperative pain, nausea, vomiting and shivering were similar in the three study groups.

摘要

在全身麻醉下行颈动脉内膜剥脱术后,与使用异氟烷相比,地氟烷和七氟烷的快速消除可能使术后神经功能评估更早进行。然而,地氟烷可能与心动过速和高血压有关,因此可能增加心血管风险。我们研究了计划接受颈动脉内膜剥脱术的患者使用异氟烷、七氟烷或地氟烷麻醉时的血流动力学和恢复特征。在心脏指数或ST段分析方面,围手术期未观察到显著差异。地氟烷和七氟烷麻醉后拔管、按指令活动和苏醒的时间比异氟烷麻醉后短。三个研究组术后疼痛、恶心、呕吐和寒战情况相似。

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