Ponomareva R B, Kavunenko T N, Kalatcheva T N, Tikhomirova-Sidorova N S, Samsonov G V
Biokhimiia. 1975 May-Jun;40(3):468-75.
Carboxymethylcellulose, carboxymethylchitin, sulfoethylcellulose and dextrane sulfate interact with pancreatic ribonuclease. In comparison with ribonuclease activity the activity of formed complexes changes differently at the stages of transesterification and hydrolysis, and at each stage the effect of polymers on ribonuclease activity essentially differs. The use of ribonuclease-dextrane sulfate complex in the reaction of uridylyl-(3' leads to 5')-cytidine synthesis demonstrated that the protein synthetic activity completely retained when hydrolytic activity was considerably suppressed.
羧甲基纤维素、羧甲基几丁质、磺基乙基纤维素和硫酸葡聚糖与胰腺核糖核酸酶相互作用。与核糖核酸酶活性相比，形成的复合物在酯交换和水解阶段的活性变化不同，并且在每个阶段聚合物对核糖核酸酶活性的影响本质上也不同。在尿苷酰基-（3'至5'）-胞苷合成反应中使用核糖核酸酶-硫酸葡聚糖复合物表明，当水解活性被显著抑制时，蛋白质合成活性完全保留。
