Matthews D C
Division of Periodontics, Faculty of Dentistry, Dalhousie University.
J Can Dent Assoc. 2000 Oct;66(9):488-91.
Recent evidence indicates that we need to change how we think about the etiology and pathogenesis of periodontal disease. Although bacteria are a necessary factor in the equation, the reaction of the host's immuno-inflammatory system is responsible for most of the destruction found in periodontal disease. Thus, it makes sense that a number of environmental and acquired factors may modify a patient's risk of developing periodontal disease. This paper reviews the scientific evidence for a number of these risk factors including age, genetics, smoking, diabetes mellitus, stress and osteoporosis.
最近的证据表明，我们需要改变对牙周病病因和发病机制的看法。虽然细菌是其中的一个必要因素，但宿主免疫炎症系统的反应才是牙周病中发现的大部分破坏的原因。因此，许多环境和后天因素可能会改变患者患牙周病的风险，这是有道理的。本文综述了包括年龄、遗传、吸烟、糖尿病、压力和骨质疏松症等多种这些风险因素的科学证据。
