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[成人斯蒂尔病相关的自身免疫性溶血性贫血]

[Autoimmune hemolytic anemia associated with adult-onset Still's disease].

作者信息

Narigasawa Y, Ono Y, Kuriya S

机构信息

Department of Internal Medicine, Kitakami Saisei-kai Hospital.

出版信息

Rinsho Ketsueki. 2000 Sep;41(9):729-32.

PMID:11070934
Abstract

A 37-year-old woman was admitted to our hospital in March 1995 because of high fever and cervical lymph node swelling. She had received prednisolone (PSL) therapy for autoimmune hemolytic anemia (AIHA). Laboratory examinations revealed increased serum levels of liver enzymes and C-reactive protein. Levels of rheumatoid factor and anti-nuclear antibody were within normal limits. On the basis of these criteria, she was diagnosed as having adult-onset Still's disease (AOSD). Although her fever ameliorated and physical symptoms disappeared immediately after a moderate dose of PSL, hemolysis recurred when attempts were made to reduce or withdraw the steroid. The patient is now receiving low-dose PSL therapy and is free of AIHA and AOSD.

摘要

一名37岁女性于1995年3月因高热和颈部淋巴结肿大入住我院。她曾因自身免疫性溶血性贫血(AIHA)接受泼尼松龙(PSL)治疗。实验室检查显示血清肝酶和C反应蛋白水平升高。类风湿因子和抗核抗体水平在正常范围内。基于这些标准,她被诊断为成人斯蒂尔病(AOSD)。尽管在给予中等剂量PSL后她的发热症状有所改善且身体症状立即消失,但在试图减少或停用类固醇时溶血复发。该患者目前正在接受低剂量PSL治疗,且未出现AIHA和AOSD。

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