Kimi K, Onodera K, Kumamoto H, Ichinohasama R, Echigo S, Ooya K
Department of Oral Pathology, Tohoku University School of Dentistry, Sendai, Japan.
Int J Oral Maxillofac Surg. 2000 Oct;29(5):366-9.
An alveolar soft-part sarcoma (ASPS) occurring in the cheek is described, with a review of the literature. The subject was a 25-year-old woman who presented with a large swelling in the left cheek. The lesion, initially diagnosed as a benign tumor on radiographic and computed tomographic examinations, was surgically excised. Histopathological examination of the mass revealed a nest-like or organoid cellular arrangement as confirmed by three-dimensional computer graphic reconstruction. The cytoplasm of the large polygonal tumor cells contained abundant diastase-resistant, PAS-positive inclusions, ultrastructurally confirmed to be crystalloid materials. The tumor cells were immunoreactive for anti-myoglobin, sarcomeric actin, and neuron-specific enolase antibodies, suggesting a myogenic origin.
本文描述了一例发生于颊部的肺泡软组织肉瘤（ASPS），并对相关文献进行了综述。患者为一名25岁女性，左侧颊部出现一个巨大肿物。该病变在X线和计算机断层扫描检查中最初被诊断为良性肿瘤，随后接受了手术切除。对肿物进行组织病理学检查，通过三维计算机图形重建证实为巢状或类器官样细胞排列。大的多边形肿瘤细胞的细胞质中含有丰富的抗淀粉酶、PAS阳性包涵体，超微结构证实为晶体物质。肿瘤细胞对抗肌红蛋白、肌节肌动蛋白和神经元特异性烯醇化酶抗体呈免疫反应，提示其起源于肌源性。
