Mitsui S, Okui A, Kominami K, Uemura H, Yamaguchi N
Department of Cell BIology, Research Institute for Neurological Diseases and Geriatrics, Kyoto Prefectural University of Medicine, Japan.
Biochim Biophys Acta. 2000 Nov 15;1494(1-2):206-10. doi: 10.1016/s0167-4781(00)00206-2.
Two splicing variants of mouse hippostasin/TLSP (PRSS20) were identified and termed brain-type and prostate-type, respectively. Mouse hippostasin/TLSP showed 76.8% identity to the human homologue. Transient expression showed that both translational products were secreted into the conditioned medium. Mouse hippostasin/TLSP was expressed preferentially in the fetal brain and the prostate, but not in the neonatal brain. The brain expressed only brain-type hippostasin/TLSP, while the prostate expressed both types.
