Cohen G N, Amols H I, Zaider M
Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA,
Int J Radiat Oncol Biol Phys. 2000 Nov 1;48(4):1251-8. doi: 10.1016/s0360-3016(00)00725-2.
We describe computer software that performs, quickly and accurately, secondary dose calculations for high-dose-rate (HDR) treatment plans, including those employed for prostate treatments.
The program takes as primary input the data file used by the HDR remote afterloader console for treatment. Dosimetric calculations are performed using the Meisberger polynomial and the anisotropy table for the HDR Iridium-192 source. For standard applicators, treatment geometry is automatically reconstructed and the dose is calculated at relevant reference point(s). Template-based treatment plans (e.g., prostate) require additional user input; the dose calculation is then performed at user-selected reference points. A total dwell time calculation for volume and planar implants using the Manchester tables was also implemented.
For fixed-geometry HDR procedures, secondary dose calculations are within 2% of the treatment plan, and results are available for review instantly. For more general applications, the calculated and planned doses are typically within 3% at the prescription isodose line. The Manchester-based dwell time calculation is within 10% of the planned time.
我们描述了一种计算机软件，它能快速、准确地对高剂量率（HDR）治疗计划进行二次剂量计算，包括用于前列腺治疗的计划。
该程序将HDR远程后装治疗控制台用于治疗的数据文件作为主要输入。使用迈斯伯格多项式和铱 - 192 HDR源的各向异性表进行剂量计算。对于标准施源器，自动重建治疗几何结构并在相关参考点计算剂量。基于模板的治疗计划（如前列腺）需要额外的用户输入；然后在用户选择的参考点进行剂量计算。还实现了使用曼彻斯特表对体积和平面植入物的总驻留时间计算。
对于固定几何结构的HDR程序，二次剂量计算在治疗计划的2%以内，结果可立即供审查。对于更一般的应用，在处方等剂量线上计算剂量与计划剂量通常在3%以内。基于曼彻斯特的驻留时间计算在计划时间的10%以内。
